For full list on PubMed click here
1: Kucharczyk MW, Derrien D, Dickenson AH, Bannister K. The Stage-Specific
Plasticity of Descending Modulatory Controls in a Rodent Model of Cancer-Induced
Bone Pain. Cancers (Basel). 2020 Nov 6;12(11):3286. doi:
10.3390/cancers12113286. PMID: 33172040; PMCID: PMC7716240.
2: Kucharczyk MW, Chisholm KI, Denk F, Dickenson AH, Bannister K, McMahon SB.
The impact of bone cancer on the peripheral encoding of mechanical pressure
stimuli. Pain. 2020 Aug;161(8):1894-1905. doi: 10.1097/j.pain.0000000000001880.
PMID: 32701848; PMCID: PMC7365668.
3: Bannister K, Dickenson AH. Central Nervous System Targets: Supraspinal
Mechanisms of Analgesia. Neurotherapeutics. 2020 Jul;17(3):839-845. doi:
10.1007/s13311-020-00887-6. PMID: 32700132; PMCID: PMC7609795.
4: Bonezzi C, Costantini A, Cruccu G, Fornasari DMM, Guardamagna V, Palmieri V,
Polati E, Zini P, Dickenson AH. Capsaicin 8% dermal patch in clinical practice:
an expert opinion. Expert Opin Pharmacother. 2020 Aug;21(11):1377-1387. doi:
10.1080/14656566.2020.1759550. Epub 2020 Jun 8. PMID: 32511032.
5: Kucharczyk MW, Chisholm KI, Denk F, Dickenson AH, Bannister K, McMahon SB.
The impact of bone cancer on the peripheral encoding of mechanical pressure
stimuli. Pain. 2020 Apr 13. doi: 10.1097/j.pain.0000000000001880. Epub ahead of
print. PMID: 32301838.
6: Dickenson AH, Patel R. Translational issues in precision medicine in
neuropathic pain. Can J Pain. 2020 Jan 23;4(1):30-38. doi:
10.1080/24740527.2020.1720502. PMID: 32258972; PMCID: PMC7077367.
7: Caraci F, Coluzzi F, Marinangeli F, Mercadante S, Rinonapoli G, Romualdi P,
Nicora M, Dickenson AH. Modulation of sensitization processes in the management
of pain and the importance of descending pathways: a role for tapentadol? Curr
Med Res Opin. 2020 Jun;36(6):1015-1024. doi: 10.1080/03007995.2020.1748876. Epub
2020 Apr 9. PMID: 32216591.
8: Yosten GL, Harada CM, Haddock C, Giancotti LA, Kolar GR, Patel R, Guo C, Chen
Z, Zhang J, Doyle TM, Dickenson AH, Samson WK, Salvemini D. GPR160 de-
orphanization reveals critical roles in neuropathic pain in rodents. J Clin
Invest. 2020 May 1;130(5):2587-2592. doi: 10.1172/JCI133270. PMID: 31999650;
PMCID: PMC7190928.
9: Dickenson AH, Navratilova E, Patel R, Porreca F, Bannister K. Supraspinal
Opioid Circuits Differentially Modulate Spinal Neuronal Responses in Neuropathic
Rats. Anesthesiology. 2020 Apr;132(4):881-894. doi:
10.1097/ALN.0000000000003120. PMID: 31977518.
10: Bannister K, Sachau J, Baron R, Dickenson AH. Neuropathic Pain: Mechanism-
Based Therapeutics. Annu Rev Pharmacol Toxicol. 2020 Jan 6;60:257-274. doi:
10.1146/annurev-pharmtox-010818-021524. PMID: 31914896.
11: Caraci F, Coluzzi F, Marinangeli F, Mercadante S, Rinonapoli G, Romualdi P,
Nicora M, Dickenson AH. Modulation of sensitization processes in the management
of pain and the importance of descending pathways: a role for tapentadol? Curr
Med Res Opin. 2020 May;36(5):I-XVII. doi: 10.1080/03007995.2019.1703664.
Retraction in: Curr Med Res Opin. 2020 Mar;36(3):523. PMID: 31822137.
12: Navratilova E, Nation K, Remeniuk B, Neugebauer V, Bannister K, Dickenson
AH, Porreca F. Selective modulation of tonic aversive qualities of neuropathic
pain by morphine in the central nucleus of the amygdala requires endogenous
opioid signaling in the anterior cingulate cortex. Pain. 2020
Mar;161(3):609-618. doi: 10.1097/j.pain.0000000000001748. PMID: 31725062; PMCID:
PMC7124010.
13: Patel R, Dickenson AH. A study of cortical and brainstem mechanisms of
diffuse noxious inhibitory controls in anaesthetised normal and neuropathic
rats. Eur J Neurosci. 2020 Feb;51(4):952-962. doi: 10.1111/ejn.14576. Epub 2019
Oct 6. PMID: 31518451; PMCID: PMC7079135.
14: Lockwood S, Dickenson AH. What goes up must come down: insights from studies
on descending controls acting on spinal pain processing. J Neural Transm
(Vienna). 2020 Apr;127(4):541-549. doi: 10.1007/s00702-019-02077-x. Epub 2019
Sep 12. PMID: 31515656; PMCID: PMC7148257.
15: Carcolé M, Kummer S, Gonçalves L, Zamanillo D, Merlos M, Dickenson AH,
Fernández-Pastor B, Cabañero D, Maldonado R. Sigma-1 receptor modulates
neuroinflammation associated with mechanical hypersensitivity and opioid
tolerance in a mouse model of osteoarthritis pain. Br J Pharmacol. 2019
Oct;176(20):3939-3955. doi: 10.1111/bph.14794. Epub 2019 Sep 12. PMID: 31332781;
PMCID: PMC6811737.
16: Romualdi P, Grilli M, Canonico PL, Collino M, Dickenson AH. Pharmacological
rationale for tapentadol therapy: a review of new evidence. J Pain Res. 2019 May
16;12:1513-1520. doi: 10.2147/JPR.S190160. PMID: 31190962; PMCID: PMC6526917.
17: Dickenson AH, Kress HG. Tapentadol: a new option for the treatment of cancer
and noncancer pains. J Pain Res. 2019 May 16;12:1509-1511. doi:
10.2147/JPR.S190171. PMID: 31190961; PMCID: PMC6526922.
18: David-Pereira A, Dickenson AH. Issues in the future development of new
analgesic drugs. Curr Opin Support Palliat Care. 2019 Jun;13(2):107-110. doi:
10.1097/SPC.0000000000000425. PMID: 30883401.
19: Phelps CE, Navratilova E, Dickenson AH, Porreca F, Bannister K. Kappa opioid
signaling in the right central amygdala causes hind paw specific loss of diffuse
noxious inhibitory controls in experimental neuropathic pain. Pain. 2019
Jul;160(7):1614-1621. doi: 10.1097/j.pain.0000000000001553. PMID: 30870321.
20: Lockwood SM, Dickenson AH. A combination pharmacotherapy of tapentadol and
pregabalin to tackle centrally driven osteoarthritis pain. Eur J Pain. 2019
Jul;23(6):1185-1195. doi: 10.1002/ejp.1386. Epub 2019 Mar 22. PMID: 30821870;
PMCID: PMC6618140.
21: Martínez-Navarro M, Lara-Mayorga IM, Negrete R, Bilecki W, Wawrzczak-
Bargieła A, Gonçalves L, Dickenson AH, Przewłocki R, Baños JE, Maldonado R.
Influence of behavioral traits in the inter-individual variability of
nociceptive, emotional and cognitive manifestations of neuropathic pain.
Neuropharmacology. 2019 Apr;148:291-304. doi: 10.1016/j.neuropharm.2019.01.012.
Epub 2019 Jan 19. PMID: 30668942.
22: Lockwood SM, Lopes DM, McMahon SB, Dickenson AH. Characterisation of
peripheral and central components of the rat monoiodoacetate model of
Osteoarthritis. Osteoarthritis Cartilage. 2019 Apr;27(4):712-722. doi:
10.1016/j.joca.2018.12.017. Epub 2019 Jan 3. PMID: 30611904; PMCID: PMC6444078.
23: Lockwood SM, Bannister K, Dickenson AH. An investigation into the
noradrenergic and serotonergic contributions of diffuse noxious inhibitory
controls in a monoiodoacetate model of osteoarthritis. J Neurophysiol. 2019 Jan
1;121(1):96-104. doi: 10.1152/jn.00613.2018. Epub 2018 Nov 21. PMID: 30461363;
PMCID: PMC6383660.
24: Patel R, Dickenson AH. Modality selective roles of pro-nociceptive spinal
5-HT<sub>2A</sub> and 5-HT<sub>3</sub> receptors in normal and neuropathic
states. Neuropharmacology. 2018 Dec;143:29-37. doi:
10.1016/j.neuropharm.2018.09.028. Epub 2018 Sep 18. PMID: 30240783; PMCID:
PMC6277848.
25: Patel R, Kucharczyk M, Montagut-Bordas C, Lockwood S, Dickenson AH.
Neuropathy following spinal nerve injury shares features with the irritable
nociceptor phenotype: A back-translational study of oxcarbazepine. Eur J Pain.
2019 Jan;23(1):183-197. doi: 10.1002/ejp.1300. Epub 2018 Aug 28. PMID: 30091265;
PMCID: PMC6396087.
26: Gomtsian L, Bannister K, Eyde N, Robles D, Dickenson AH, Porreca F,
Navratilova E. Morphine effects within the rodent anterior cingulate cortex and
rostral ventromedial medulla reveal separable modulation of affective and
sensory qualities of acute or chronic pain. Pain. 2018 Dec;159(12):2512-2521.
doi: 10.1097/j.pain.0000000000001355. PMID: 30086115; PMCID: PMC6320264.
27: Dickenson AH, Patel R. Sense and sensibility-logical approaches to profiling
in animal models. Pain. 2018 Jul;159(7):1426-1428. doi:
10.1097/j.pain.0000000000001245. PMID: 29916961; PMCID: PMC6027960.
28: Patel R, Qu C, Xie JY, Porreca F, Dickenson AH. Selective deficiencies in
descending inhibitory modulation in neuropathic rats: implications for enhancing
noradrenergic tone. Pain. 2018 Sep;159(9):1887-1899. doi:
10.1097/j.pain.0000000000001300. PMID: 29863529; PMCID: PMC6095727.
29: Dickenson AH, Farquhar-Smith P. Editorial for Pain: Cancer in 2018. Curr
Opin Support Palliat Care. 2018 Jun;12(2):101. doi:
10.1097/SPC.0000000000000344. PMID: 29608466.
30: Dickenson AH, Bannister K. Editorial for Pain: Nonmalignant Diseases in
2018. Curr Opin Support Palliat Care. 2018 Jun;12(2):131. doi:
10.1097/SPC.0000000000000343. PMID: 29608465.
31: Dawes JM, Weir GA, Middleton SJ, Patel R, Chisholm KI, Pettingill P, Peck
LJ, Sheridan J, Shakir A, Jacobson L, Gutierrez-Mecinas M, Galino J, Walcher J,
Kühnemund J, Kuehn H, Sanna MD, Lang B, Clark AJ, Themistocleous AC, Iwagaki N,
West SJ, Werynska K, Carroll L, Trendafilova T, Menassa DA, Giannoccaro MP,
Coutinho E, Cervellini I, Tewari D, Buckley C, Leite MI, Wildner H, Zeilhofer
HU, Peles E, Todd AJ, McMahon SB, Dickenson AH, Lewin GR, Vincent A, Bennett DL.
Immune or Genetic-Mediated Disruption of CASPR2 Causes Pain Hypersensitivity Due
to Enhanced Primary Afferent Excitability. Neuron. 2018 Feb
21;97(4):806-822.e10. doi: 10.1016/j.neuron.2018.01.033. Epub 2018 Feb 8. PMID:
29429934; PMCID: PMC6011627.
32: Dalmolin GD, Bannister K, Gonçalves L, Sikandar S, Patel R, Cordeiro MDN,
Gomez MV, Ferreira J, Dickenson AH. Effect of the spider toxin Tx3-3 on spinal
processing of sensory information in naive and neuropathic rats: an in vivo
electrophysiological study. Pain Rep. 2017 Jul 6;2(4):e610. doi:
10.1097/PR9.0000000000000610. PMID: 29392225; PMCID: PMC5741365.
33: Dickenson AH. Holding down the pain. Brain. 2018 Jan 1;141(1):5-6. doi:
10.1093/brain/awx334. PMID: 29325048; PMCID: PMC5837699.
34: Bannister K, Qu C, Navratilova E, Oyarzo J, Xie JY, King T, Dickenson AH,
Porreca F. Multiple sites and actions of gabapentin-induced relief of ongoing
experimental neuropathic pain. Pain. 2017 Dec;158(12):2386-2395. doi:
10.1097/j.pain.0000000000001040. PMID: 28832395; PMCID: PMC5681862.
35: Sikandar S, West SJ, McMahon SB, Bennett DL, Dickenson AH. Sensory
processing of deep tissue nociception in the rat spinal cord and thalamic
ventrobasal complex. Physiol Rep. 2017 Jul;5(14):e13323. doi:
10.14814/phy2.13323. PMID: 28720713; PMCID: PMC5532477.
36: Bannister K, Kucharczyk M, Dickenson AH. Hopes for the Future of Pain
Control. Pain Ther. 2017 Dec;6(2):117-128. doi: 10.1007/s40122-017-0073-6. Epub
2017 May 23. PMID: 28536900; PMCID: PMC5693804.
37: Bannister K, Dickenson AH. The plasticity of descending controls in pain:
translational probing. J Physiol. 2017 Jul 1;595(13):4159-4166. doi:
10.1113/JP274165. Epub 2017 May 26. PMID: 28387936; PMCID: PMC5491855.
38: Dickenson AH, Bannister K. Editorial. Curr Opin Support Palliat Care. 2017
Jun;11(2):105. doi: 10.1097/SPC.0000000000000268. PMID: 28375884.
39: Patel R, Montagut-Bordas C, Dickenson AH. Calcium channel modulation as a
target in chronic pain control. Br J Pharmacol. 2018 Jun;175(12):2173-2184. doi:
10.1111/bph.13789. Epub 2017 Apr 26. PMID: 28320042; PMCID: PMC5980588.
40: Colloca L, Ludman T, Bouhassira D, Baron R, Dickenson AH, Yarnitsky D,
Freeman R, Truini A, Attal N, Finnerup NB, Eccleston C, Kalso E, Bennett DL,
Dworkin RH, Raja SN. Neuropathic pain. Nat Rev Dis Primers. 2017 Feb 16;3:17002.
doi: 10.1038/nrdp.2017.2. PMID: 28205574; PMCID: PMC5371025.
41: Bannister K, Lockwood S, Goncalves L, Patel R, Dickenson AH. An
investigation into the inhibitory function of serotonin in diffuse noxious
inhibitory controls in the neuropathic rat. Eur J Pain. 2017 Apr;21(4):750-760.
doi: 10.1002/ejp.979. Epub 2016 Nov 28. PMID: 27891703.
42: Langford RM, Knaggs R, Farquhar-Smith P, Dickenson AH. Is tapentadol
different from classical opioids? A review of the evidence. Br J Pain. 2016
Nov;10(4):217-221. doi: 10.1177/2049463716657363. Epub 2016 Jul 25. PMID:
27867511; PMCID: PMC5102094.
43: Sikandar S, Gustavsson Y, Marino MJ, Dickenson AH, Yaksh TL, Sorkin LS,
Ramachandran R. Effects of intraplantar botulinum toxin-B on carrageenan-induced
changes in nociception and spinal phosphorylation of GluA1 and Akt. Eur J
Neurosci. 2016 Jul;44(1):1714-22. doi: 10.1111/ejn.13261. Epub 2016 May 19.
PMID: 27108664; PMCID: PMC4931962.
44: Patel R, Dickenson AH. Neuronal hyperexcitability in the ventral posterior
thalamus of neuropathic rats: modality selective effects of pregabalin. J
Neurophysiol. 2016 Jul 1;116(1):159-70. doi: 10.1152/jn.00237.2016. Epub 2016
Apr 20. PMID: 27098028; PMCID: PMC4961752.
45: Liang M, Lee MC, O'Neill J, Dickenson AH, Iannetti GD. Brain potentials
evoked by intraepidermal electrical stimuli reflect the central sensitization of
nociceptive pathways. J Neurophysiol. 2016 Aug 1;116(2):286-95. doi:
10.1152/jn.00013.2016. Epub 2016 Apr 20. PMID: 27098022; PMCID: PMC4969393.
46: Patel R, Dickenson AH. Mechanisms of the gabapentinoids and α 2 δ-1 calcium
channel subunit in neuropathic pain. Pharmacol Res Perspect. 2016 Feb
27;4(2):e00205. doi: 10.1002/prp2.205. PMID: 27069626; PMCID: PMC4804325.
47: Bannister K, Dickenson AH. What do monoamines do in pain modulation? Curr
Opin Support Palliat Care. 2016 Jun;10(2):143-8. doi:
10.1097/SPC.0000000000000207. PMID: 27043287; PMCID: PMC5604728.
48: Bannister K, Dickenson AH. What the brain tells the spinal cord. Pain. 2016
Oct;157(10):2148-51. doi: 10.1097/j.pain.0000000000000568. PMID: 27023423.
49: Dickenson AH, Baron R. Making sense of sensory profiles. Pain. 2016
Jun;157(6):1177-8. doi: 10.1097/j.pain.0000000000000560. PMID: 26989806.
50: Sikandar S, Aasvang EK, Dickenson AH. Scratching the surface: the processing
of pain from deep tissues. Pain Manag. 2016 Apr;6(2):95-102. doi:
10.2217/pmt.15.50. Epub 2016 Mar 14. PMID: 26974398.
51: Baron R, Binder A, Attal N, Casale R, Dickenson AH, Treede RD. Neuropathic
low back pain in clinical practice. Eur J Pain. 2016 Jul;20(6):861-73. doi:
10.1002/ejp.838. Epub 2016 Mar 2. PMID: 26935254; PMCID: PMC5069616.
52: Haley JE, Dickenson AH. Evidence for spinal N-methyl-d-aspartate receptor
involvement in prolonged chemical nociception in the rat. Brain Res. 2016 Aug
15;1645:58-60. doi: 10.1016/j.brainres.2016.02.001. Epub 2016 Feb 15. PMID:
26892026.
53: Dickenson AH. Special 10th anniversary editorial: pain. Curr Opin Support
Palliat Care. 2016 Mar;10(1):2. doi: 10.1097/SPC.0000000000000193. PMID:
26780524.
54: Falk S, Bannister K, Dickenson AH. Cancer pain physiology. Br J Pain. 2014
Nov;8(4):154-62. doi: 10.1177/2049463714545136. PMID: 26516549; PMCID:
PMC4616725.
55: Patel R, Brice NL, Lewis RJ, Dickenson AH. Ionic mechanisms of spinal
neuronal cold hypersensitivity in ciguatera. Eur J Neurosci. 2015
Dec;42(11):3004-11. doi: 10.1111/ejn.13098. Epub 2015 Nov 13. PMID: 26454262;
PMCID: PMC4744673.
56: Rahman W, Patel R, Dickenson AH. Electrophysiological evidence for voltage-
gated calcium channel 2 (Cav2) modulation of mechano- and thermosensitive spinal
neuronal responses in a rat model of osteoarthritis. Neuroscience. 2015 Oct
1;305:76-85. doi: 10.1016/j.neuroscience.2015.07.073. Epub 2015 Aug 4. PMID:
26247695; PMCID: PMC4564012.
57: DʼMello R, Sand CA, Pezet S, Leiper JM, Gaurilcikaite E, McMahon SB,
Dickenson AH, Nandi M. Dimethylarginine dimethylaminohydrolase 1 is involved in
spinal nociceptive plasticity. Pain. 2015 Oct;156(10):2052-60. doi:
10.1097/j.pain.0000000000000269. PMID: 26098438; PMCID: PMC4770343.
58: O'Neill J, Sikandar S, McMahon SB, Dickenson AH. Human psychophysics and
rodent spinal neurones exhibit peripheral and central mechanisms of inflammatory
pain in the UVB and UVB heat rekindling models. J Physiol. 2015 Sep
1;593(17):4029-42. doi: 10.1113/JP270294. Epub 2015 Aug 12. PMID: 26047369;
PMCID: PMC4575584.
59: Bannister K, Patel R, Goncalves L, Townson L, Dickenson AH. Diffuse noxious
inhibitory controls and nerve injury: restoring an imbalance between descending
monoamine inhibitions and facilitations. Pain. 2015 Sep;156(9):1803-11. doi:
10.1097/j.pain.0000000000000240. PMID: 26010460.
60: West SJ, Bannister K, Dickenson AH, Bennett DL. Circuitry and plasticity of
the dorsal horn--toward a better understanding of neuropathic pain.
Neuroscience. 2015 Aug 6;300:254-75. doi: 10.1016/j.neuroscience.2015.05.020.
Epub 2015 May 16. PMID: 25987204.
61: Dickenson AH, Farquhar-Smith PW. Pain: cancer. Curr Opin Support Palliat
Care. 2015 Jun;9(2):97. doi: 10.1097/SPC.0000000000000141. PMID: 25923340.
62: Rahman W, Dickenson AH. Pain: nonmalignant disease. Curr Opin Support
Palliat Care. 2015 Jun;9(2):122-3. doi: 10.1097/SPC.0000000000000138. PMID:
25872122.
63: Patel R, Rutten K, Valdor M, Schiene K, Wigge S, Schunk S, Damann N,
Christoph T, Dickenson AH. Electrophysiological characterization of activation
state-dependent Ca(v)2 channel antagonist TROX-1 in spinal nerve injured rats.
Neuroscience. 2015 Jun 25;297:47-57. doi: 10.1016/j.neuroscience.2015.03.057.
Epub 2015 Apr 1. PMID: 25839150; PMCID: PMC4436437.
64: Rahman W, Dickenson AH. Osteoarthritis-dependent changes in antinociceptive
action of Nav1.7 and Nav1.8 sodium channel blockers: An in vivo
electrophysiological study in the rat. Neuroscience. 2015 Jun 4;295:103-16. doi:
10.1016/j.neuroscience.2015.03.042. Epub 2015 Mar 25. PMID: 25818052; PMCID:
PMC4414363.
65: Rahman W, Dickenson AH. Emerging targets and therapeutic approaches for the
treatment of osteoarthritis pain. Curr Opin Support Palliat Care. 2015
Jun;9(2):124-30. doi: 10.1097/SPC.0000000000000125. PMID: 25730180.
66: Falk S, Schwab SD, Frøsig-Jørgensen M, Clausen RP, Dickenson AH, Heegaard
AM. P2X7 receptor-mediated analgesia in cancer-induced bone pain. Neuroscience.
2015 Apr 16;291:93-105. doi: 10.1016/j.neuroscience.2015.02.011. Epub 2015 Feb
14. PMID: 25686524.
67: Gonçalves L, Friend LV, Dickenson AH. The influence of μ-opioid and
noradrenaline reuptake inhibition in the modulation of pain responsive neurones
in the central amygdala by tapentadol in rats with neuropathy. Eur J Pharmacol.
2015 Feb 15;749:151-60. doi: 10.1016/j.ejphar.2014.11.032. Epub 2015 Jan 6.
PMID: 25576174; PMCID: PMC4339205.
68: Rahman W, Dickenson AH. Antinociceptive effects of lacosamide on spinal
neuronal and behavioural measures of pain in a rat model of osteoarthritis.
Arthritis Res Ther. 2014 Dec 23;16(6):509. doi: 10.1186/s13075-014-0509-x. PMID:
25533381; PMCID: PMC4308925.
69: Little JW, Ford A, Symons-Liguori AM, Chen Z, Janes K, Doyle T, Xie J,
Luongo L, Tosh DK, Maione S, Bannister K, Dickenson AH, Vanderah TW, Porreca F,
Jacobson KA, Salvemini D. Endogenous adenosine A3 receptor activation
selectively alleviates persistent pain states. Brain. 2015 Jan;138(Pt 1):28-35.
doi: 10.1093/brain/awu330. Epub 2014 Nov 19. PMID: 25414036; PMCID: PMC4285194.
70: Baron R, Dickenson AH. Neuropathic pain: precise sensory profiling improves
treatment and calls for back-translation. Pain. 2014 Nov;155(11):2215-7. doi:
10.1016/j.pain.2014.08.021. Epub 2014 Aug 26. PMID: 25168667.
71: Patel R, Gonçalves L, Leveridge M, Mack SR, Hendrick A, Brice NL, Dickenson
AH. Anti-hyperalgesic effects of a novel TRPM8 agonist in neuropathic rats: a
comparison with topical menthol. Pain. 2014 Oct;155(10):2097-107. doi:
10.1016/j.pain.2014.07.022. Epub 2014 Jul 30. PMID: 25083927; PMCID: PMC4220012.
72: Falk S, Ipsen DH, Appel CK, Ugarak A, Durup D, Dickenson AH, Heegaard AM.
Randall Selitto pressure algometry for assessment of bone-related pain in rats.
Eur J Pain. 2015 Mar;19(3):305-12. doi: 10.1002/ejp.547. PMID: 25057115.
73: Bannister K, Lee YS, Goncalves L, Porreca F, Lai J, Dickenson AH.
Neuropathic plasticity in the opioid and non-opioid actions of dynorphin A
fragments and their interactions with bradykinin B2 receptors on neuronal
activity in the rat spinal cord. Neuropharmacology. 2014 Oct;85:375-83. doi:
10.1016/j.neuropharm.2014.06.005. Epub 2014 Jun 14. PMID: 24937046; PMCID:
PMC4873257.
74: Falk S, Patel R, Heegaard A, Mercadante S, Dickenson AH. Spinal neuronal
correlates of tapentadol analgesia in cancer pain: a back-translational
approach. Eur J Pain. 2015 Feb;19(2):152-8. doi: 10.1002/ejp.530. Epub 2014 Jun
11. PMID: 24917026.
75: Falk S, Dickenson AH. Pain and nociception: mechanisms of cancer-induced
bone pain. J Clin Oncol. 2014 Jun 1;32(16):1647-54. doi:
10.1200/JCO.2013.51.7219. Epub 2014 May 5. PMID: 24799469.
76: Gilron I, Dickenson AH. Emerging drugs for neuropathic pain. Expert Opin
Emerg Drugs. 2014 Sep;19(3):329-41. doi: 10.1517/14728214.2014.915025. Epub 2014
May 3. PMID: 24793304.
77: Rahman W, Dickenson AH. Pain: nonmalignant disease. Curr Opin Support
Palliat Care. 2014 Sep;8(3):314-5. doi: 10.1097/SPC.0000000000000052. PMID:
24722476.
78: Thakur M, Dickenson AH, Baron R. Osteoarthritis pain: nociceptive or
neuropathic? Nat Rev Rheumatol. 2014 Jun;10(6):374-80. doi:
10.1038/nrrheum.2014.47. Epub 2014 Apr 1. PMID: 24686507.
79: Patel R, Gonçalves L, Newman R, Jiang FL, Goldby A, Reeve J, Hendrick A,
Teall M, Hannah D, Almond S, Brice N, Dickenson AH. Novel TRPM8 antagonist
attenuates cold hypersensitivity after peripheral nerve injury in rats. J
Pharmacol Exp Ther. 2014 Apr;349(1):47-55. doi: 10.1124/jpet.113.211243. Epub
2014 Jan 28. PMID: 24472724.
80: Lana B, Schlick B, Martin S, Pratt WS, Page KM, Goncalves L, Rahman W,
Dickenson AH, Bauer CS, Dolphin AC. Differential upregulation in DRG neurons of
an α2δ-1 splice variant with a lower affinity for gabapentin after peripheral
sensory nerve injury. Pain. 2014 Mar;155(3):522-33. doi:
10.1016/j.pain.2013.12.001. Epub 2013 Dec 6. PMID: 24315988; PMCID: PMC3988960.
81: Dickenson AH, Kehlet H. Can we stop pain before it starts? Pain. 2014
Feb;155(2):208-9. doi: 10.1016/j.pain.2013.11.016. Epub 2013 Nov 27. PMID:
24291652.
82: Patel R, Bauer CS, Nieto-Rostro M, Margas W, Ferron L, Chaggar K, Crews K,
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deletion affects somatosensory neuron function and delays mechanical
hypersensitivity in response to peripheral nerve damage. J Neurosci. 2013 Oct
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83: Hirsch SJ, Dickenson AH. Morphine sensitivity of spinal neurons in the
chronic constriction injury neuropathic rat pain model. Neurosci Lett. 2014 Mar
6;562:97-101. doi: 10.1016/j.neulet.2013.10.007. Epub 2013 Oct 12. PMID:
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84: Dickenson AH. Commentary on: Opioid and noradrenergic contributions of
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85: Gilron I, Jensen TS, Dickenson AH. Combination pharmacotherapy for
management of chronic pain: from bench to bedside. Lancet Neurol. 2013
Nov;12(11):1084-95. doi: 10.1016/S1474-4422(13)70193-5. Epub 2013 Sep 25. PMID:
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86: Baron R, Hans G, Dickenson AH. Peripheral input and its importance for
central sensitization. Ann Neurol. 2013 Nov;74(5):630-6. doi: 10.1002/ana.24017.
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87: Tesfaye S, Boulton AJ, Dickenson AH. Mechanisms and management of diabetic
painful distal symmetrical polyneuropathy. Diabetes Care. 2013
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88: Rahman W, Dickenson AH. Voltage gated sodium and calcium channel blockers
for the treatment of chronic inflammatory pain. Neurosci Lett. 2013 Dec 17;557
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89: Sikandar S, Dickenson AH. II. No need for translation when the same language
is spoken. Br J Anaesth. 2013 Jul;111(1):3-6. doi: 10.1093/bja/aet210. PMID:
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90: Sikandar S, Ronga I, Iannetti GD, Dickenson AH. Neural coding of nociceptive
stimuli-from rat spinal neurones to human perception. Pain. 2013
Aug;154(8):1263-73. doi: 10.1016/j.pain.2013.03.041. Epub 2013 Apr 6. PMID:
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91: Currie GL, Delaney A, Bennett MI, Dickenson AH, Egan KJ, Vesterinen HM, Sena
ES, Macleod MR, Colvin LA, Fallon MT. Animal models of bone cancer pain:
systematic review and meta-analyses. Pain. 2013 Jun;154(6):917-26. doi:
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92: Eijkelkamp N, Linley JE, Torres JM, Bee L, Dickenson AH, Gringhuis M, Minett
MS, Hong GS, Lee E, Oh U, Ishikawa Y, Zwartkuis FJ, Cox JJ, Wood JN. A role for
Piezo2 in EPAC1-dependent mechanical allodynia. Nat Commun. 2013;4:1682. doi:
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93: Sikandar S, Patel R, Patel S, Sikander S, Bennett DL, Dickenson AH. Genes,
molecules and patients--emerging topics to guide clinical pain research. Eur J
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94: Burnham LJ, Dickenson AH. The antinociceptive effect of milnacipran in the
monosodium iodoacetate model of osteoarthritis pain and its relation to changes
in descending inhibition. J Pharmacol Exp Ther. 2013 Mar;344(3):696-707. doi:
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95: O'Neill J, Brock C, Olesen AE, Andresen T, Nilsson M, Dickenson AH.
Unravelling the mystery of capsaicin: a tool to understand and treat pain.
Pharmacol Rev. 2012 Oct;64(4):939-71. doi: 10.1124/pr.112.006163. PMID:
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96: Gonçalves L, Dickenson AH. Asymmetric time-dependent activation of right
central amygdala neurones in rats with peripheral neuropathy and pregabalin
modulation. Eur J Neurosci. 2012 Nov;36(9):3204-13. doi:
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97: Passmore GM, Reilly JM, Thakur M, Keasberry VN, Marsh SJ, Dickenson AH,
Brown DA. Functional significance of M-type potassium channels in nociceptive
cutaneous sensory endings. Front Mol Neurosci. 2012 May 14;5:63. doi:
10.3389/fnmol.2012.00063. PMID: 22593734; PMCID: PMC3351001.
98: Sikandar S, Bannister K, Dickenson AH. Brainstem facilitations and
descending serotonergic controls contribute to visceral nociception but not
pregabalin analgesia in rats. Neurosci Lett. 2012 Jun 21;519(1):31-6. doi:
10.1016/j.neulet.2012.05.009. Epub 2012 May 9. PMID: 22579856; PMCID:
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99: Minett MS, Nassar MA, Clark AK, Passmore G, Dickenson AH, Wang F, Malcangio
M, Wood JN. Distinct Nav1.7-dependent pain sensations require different sets of
sensory and sympathetic neurons. Nat Commun. 2012 Apr 24;3:791. doi:
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100: Thakur M, Rahman W, Hobbs C, Dickenson AH, Bennett DL. Characterisation of
a peripheral neuropathic component of the rat monoiodoacetate model of
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101: Bannister K, Dickenson AH. The double cross of morphine: Stopping OIH in
its tracks. Ann Palliat Med. 2012 Apr;1(1):4-5. doi:
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102: Sikandar S, Dickenson AH. Visceral pain: the ins and outs, the ups and
downs. Curr Opin Support Palliat Care. 2012 Mar;6(1):17-26. doi:
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103: Neziri AY, Dickenmann M, Scaramozzino P, Andersen OK, Arendt-Nielsen L,
Dickenson AH, Curatolo M. Effect of intravenous tropisetron on modulation of
pain and central hypersensitivity in chronic low back pain patients. Pain. 2012
Feb;153(2):311-8. doi: 10.1016/j.pain.2011.10.008. Epub 2011 Nov 17. PMID:
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104: Marchand F, D'Mello R, Yip PK, Calvo M, Muller E, Pezet S, Dickenson AH,
McMahon SB. Specific involvement of atypical PKCζ/PKMζ in spinal persistent
nociceptive processing following peripheral inflammation in rat. Mol Pain. 2011
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105: Dickenson AH, Baron R. Descending controls: insurance against pain? Pain.
2011 Dec;152(12):2677-8. doi: 10.1016/j.pain.2011.07.003. Epub 2011 Aug 15.
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106: Sikandar S, Dickenson AH. Pregabalin modulation of spinal and brainstem
visceral nociceptive processing. Pain. 2011 Oct;152(10):2312-22. doi:
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107: Dickenson AH. Neuropathic Pain. Rev Pain. 2011 Jun;5(2):1-2. doi:
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108: Rahman W, Dickenson AH. Recent Developments in Neuropathic Pain Mechanisms:
Implications for Treatment. Rev Pain. 2011 Jun;5(2):21-5. doi:
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109: Bannister K, Sikandar S, Bauer CS, Dolphin AC, Porreca F, Dickenson AH.
Pregabalin suppresses spinal neuronal hyperexcitability and visceral
hypersensitivity in the absence of peripheral pathophysiology. Anesthesiology.
2011 Jul;115(1):144-52. doi: 10.1097/ALN.0b013e31821f6545. PMID: 21602662;
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110: D'Mello R, Marchand F, Pezet S, McMahon SB, Dickenson AH. Perturbing PSD-95
interactions with NR2B-subtype receptors attenuates spinal nociceptive
plasticity and neuropathic pain. Mol Ther. 2011 Oct;19(10):1780-92. doi:
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111: Rahman W, Bannister K, Bee LA, Dickenson AH. A pronociceptive role for the
5-HT2 receptor on spinal nociceptive transmission: an in vivo
electrophysiological study in the rat. Brain Res. 2011 Mar 25;1382:29-36. doi:
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112: Bee LA, Bannister K, Rahman W, Dickenson AH. Mu-opioid and noradrenergic
α(2)-adrenoceptor contributions to the effects of tapentadol on spinal
electrophysiological measures of nociception in nerve-injured rats. Pain. 2011
Jan;152(1):131-9. doi: 10.1016/j.pain.2010.10.004. Epub 2010 Nov 5. PMID:
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113: Neziri AY, Scaramozzino P, Andersen OK, Dickenson AH, Arendt-Nielsen L,
Curatolo M. Reference values of mechanical and thermal pain tests in a pain-free
population. Eur J Pain. 2011 Apr;15(4):376-83. doi:
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114: Kaan TK, Yip PK, Patel S, Davies M, Marchand F, Cockayne DA, Nunn PA,
Dickenson AH, Ford AP, Zhong Y, Malcangio M, McMahon SB. Systemic blockade of
P2X3 and P2X2/3 receptors attenuates bone cancer pain behaviour in rats. Brain.
2010 Sep;133(9):2549-64. doi: 10.1093/brain/awq194. PMID: 20802203.
115: Asante CO, Dickenson AH. Descending serotonergic facilitation mediated by
spinal 5-HT3 receptors engages spinal rapamycin-sensitive pathways in the rat.
Neurosci Lett. 2010 Oct 29;484(2):108-12. doi: 10.1016/j.neulet.2010.08.024.
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116: Asante CO, Wallace VC, Dickenson AH. Mammalian target of rapamycin
signaling in the spinal cord is required for neuronal plasticity and behavioral
hypersensitivity associated with neuropathy in the rat. J Pain. 2010
Dec;11(12):1356-67. doi: 10.1016/j.jpain.2010.03.013. Epub 2010 May 8. PMID:
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117: Bauer CS, Rahman W, Tran-van-Minh A, Lujan R, Dickenson AH, Dolphin AC. The
anti-allodynic alpha(2)delta ligand pregabalin inhibits the trafficking of the
calcium channel alpha(2)delta-1 subunit to presynaptic terminals in vivo.
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118: Bannister K, Dickenson AH. Opioid hyperalgesia. Curr Opin Support Palliat
Care. 2010 Mar;4(1):1-5. doi: 10.1097/SPC.0b013e328335ddfe. PMID: 20019618.
119: Harvey VL, Caley A, Müller UC, Harvey RJ, Dickenson AH. A Selective Role
for alpha3 Subunit Glycine Receptors in Inflammatory Pain. Front Mol Neurosci.
2009 Nov 4;2:14. doi: 10.3389/neuro.02.014.2009. PMID: 19915732; PMCID:
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120: Bannister K, Bee LA, Dickenson AH. Preclinical and early clinical
investigations related to monoaminergic pain modulation. Neurotherapeutics. 2009
Oct;6(4):703-12. doi: 10.1016/j.nurt.2009.07.009. PMID: 19789074; PMCID:
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121: Rahman W, Bauer CS, Bannister K, Vonsy JL, Dolphin AC, Dickenson AH.
Descending serotonergic facilitation and the antinociceptive effects of
pregabalin in a rat model of osteoarthritic pain. Mol Pain. 2009 Aug 7;5:45.
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122: Bee LA, Dickenson AH. Effects of lacosamide, a novel sodium channel
modulator, on dorsal horn neuronal responses in a rat model of neuropathy.
Neuropharmacology. 2009 Sep;57(4):472-9. doi: 10.1016/j.neuropharm.2009.06.021.
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123: Neziri AY, Andersen OK, Petersen-Felix S, Radanov B, Dickenson AH,
Scaramozzino P, Arendt-Nielsen L, Curatolo M. The nociceptive withdrawal reflex:
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Feb;14(2):134-41. doi: 10.1016/j.ejpain.2009.04.010. Epub 2009 Jun 7. PMID:
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124: Asante CO, Wallace VC, Dickenson AH. Formalin-induced behavioural
hypersensitivity and neuronal hyperexcitability are mediated by rapid protein
synthesis at the spinal level. Mol Pain. 2009 Jun 7;5:27. doi:
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125: Harvey VL, Dickenson AH. Behavioural and electrophysiological
characterisation of experimentally induced osteoarthritis and neuropathy in
C57Bl/6 mice. Mol Pain. 2009 Apr 20;5:18. doi: 10.1186/1744-8069-5-18. PMID:
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126: Bauer CS, Nieto-Rostro M, Rahman W, Tran-Van-Minh A, Ferron L, Douglas L,
Kadurin I, Sri Ranjan Y, Fernandez-Alacid L, Millar NS, Dickenson AH, Lujan R,
Dolphin AC. The increased trafficking of the calcium channel subunit
alpha2delta-1 to presynaptic terminals in neuropathic pain is inhibited by the
alpha2delta ligand pregabalin. J Neurosci. 2009 Apr 1;29(13):4076-88. doi:
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127: Nguyen D, Deng P, Matthews EA, Kim DS, Feng G, Dickenson AH, Xu ZC, Luo ZD.
Enhanced pre-synaptic glutamate release in deep-dorsal horn contributes to
calcium channel alpha-2-delta-1 protein-mediated spinal sensitization and
behavioral hypersensitivity. Mol Pain. 2009 Feb 12;5:6. doi:
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128: Bee LA, Dickenson AH. The importance of the descending monoamine system for
the pain experience and its treatment. F1000 Med Rep. 2009 Oct 29;1:83. doi:
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129: Vonsy JL, Ghandehari J, Dickenson AH. Differential analgesic effects of
morphine and gabapentin on behavioural measures of pain and disability in a
model of osteoarthritis pain in rats. Eur J Pain. 2009 Sep;13(8):786-93. doi:
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130: Bee LA, Dickenson AH. Descending facilitation from the brainstem determines
behavioural and neuronal hypersensitivity following nerve injury and efficacy of
pregabalin. Pain. 2008 Nov 15;140(1):209-23. doi: 10.1016/j.pain.2008.08.008.
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131: Harvey VL, Dickenson AH. Mechanisms of pain in nonmalignant disease. Curr
Opin Support Palliat Care. 2008 Jun;2(2):133-9. doi:
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132: Abrahamsen B, Zhao J, Asante CO, Cendan CM, Marsh S, Martinez-Barbera JP,
Nassar MA, Dickenson AH, Wood JN. The cell and molecular basis of mechanical,
cold, and inflammatory pain. Science. 2008 Aug 1;321(5889):702-5. doi:
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133: Gordon-Williams RM, Dickenson AH. Central neuronal mechanisms in cancer-
induced bone pain. Curr Opin Support Palliat Care. 2007 Apr;1(1):6-10. doi:
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134: Ahmedzai SH, Gralla RJ, Dickenson AH. An introduction to Current Opinion in
Supportive and Palliative Care. Curr Opin Support Palliat Care. 2007
Apr;1(1):1-2. doi: 10.1097/SPC.0b013e32814e6c70. PMID: 18660715.
135: Maratou K, Wallace VC, Hasnie FS, Okuse K, Hosseini R, Jina N, Blackbeard
J, Pheby T, Orengo C, Dickenson AH, McMahon SB, Rice AS. Comparison of dorsal
root ganglion gene expression in rat models of traumatic and HIV-associated
neuropathic pain. Eur J Pain. 2009 Apr;13(4):387-98. doi:
10.1016/j.ejpain.2008.05.011. Epub 2008 Jul 7. PMID: 18606552; PMCID:
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136: Urch CE, Dickenson AH. Neuropathic pain in cancer. Eur J Cancer. 2008
May;44(8):1091-6. doi: 10.1016/j.ejca.2008.03.015. PMID: 18492553.
137: Rahman W, Suzuki R, Hunt SP, Dickenson AH. Selective ablation of dorsal
horn NK1 expressing cells reveals a modulation of spinal alpha2-adrenergic
inhibition of dorsal horn neurones. Neuropharmacology. 2008 Jun;54(8):1208-14.
doi: 10.1016/j.neuropharm.2008.03.014. Epub 2008 Apr 8. PMID: 18462764.
138: Pezet S, Marchand F, D'Mello R, Grist J, Clark AK, Malcangio M, Dickenson
AH, Williams RJ, McMahon SB. Phosphatidylinositol 3-kinase is a key mediator of
central sensitization in painful inflammatory conditions. J Neurosci. 2008 Apr
16;28(16):4261-70. doi: 10.1523/JNEUROSCI.5392-07.2008. PMID: 18417706; PMCID:
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139: D'Mello R, Dickenson AH. Spinal cord mechanisms of pain. Br J Anaesth. 2008
Jul;101(1):8-16. doi: 10.1093/bja/aen088. Epub 2008 Apr 15. PMID: 18417503.
140: Perrot S, Dickenson AH, Bennett RM. Fibromyalgia: harmonizing science with
clinical practice considerations. Pain Pract. 2008 May-Jun;8(3):177-89. doi:
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141: Rahman W, D'Mello R, Dickenson AH. Peripheral nerve injury-induced changes
in spinal alpha(2)-adrenoceptor-mediated modulation of mechanically evoked
dorsal horn neuronal responses. J Pain. 2008 Apr;9(4):350-9. doi:
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142: Matthews EA, Bee LA, Stephens GJ, Dickenson AH. The Cav2.3 calcium channel
antagonist SNX-482 reduces dorsal horn neuronal responses in a rat model of
chronic neuropathic pain. Eur J Neurosci. 2007 Jun;25(12):3561-9. doi:
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143: Bee LA, Dickenson AH. Rostral ventromedial medulla control of spinal
sensory processing in normal and pathophysiological states. Neuroscience. 2007
Jul 13;147(3):786-93. doi: 10.1016/j.neuroscience.2007.05.004. Epub 2007 Jun 14.
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144: Altier C, Dale CS, Kisilevsky AE, Chapman K, Castiglioni AJ, Matthews EA,
Evans RM, Dickenson AH, Lipscombe D, Vergnolle N, Zamponi GW. Differential role
of N-type calcium channel splice isoforms in pain. J Neurosci. 2007 Jun
13;27(24):6363-73. doi: 10.1523/JNEUROSCI.0307-07.2007. PMID: 17567797; PMCID:
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145: Rahman W, Sikandar S, Suzuki R, Hunt SP, Dickenson AH. Superficial NK1
expressing spinal dorsal horn neurones modulate inhibitory neurotransmission
mediated by spinal GABA(A) receptors. Neurosci Lett. 2007 Jun 4;419(3):278-83.
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146: Rojas-Piloni G, Dickenson AH, Condés-Lara M. Superficial dorsal horn
neurons with double spike activity in the rat. Neurosci Lett. 2007 May
29;419(2):147-52. doi: 10.1016/j.neulet.2007.04.032. Epub 2007 Apr 18. PMID:
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147: Hasnie FS, Breuer J, Parker S, Wallace V, Blackbeard J, Lever I,
Kinchington PR, Dickenson AH, Pheby T, Rice AS. Further characterization of a
rat model of varicella zoster virus-associated pain: Relationship between
mechanical hypersensitivity and anxiety-related behavior, and the influence of
analgesic drugs. Neuroscience. 2007 Feb 23;144(4):1495-508. doi:
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148: Dickenson AH, Ghandehari J. Anti-convulsants and anti-depressants. Handb
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149: Foulkes T, Nassar MA, Lane T, Matthews EA, Baker MD, Gerke V, Okuse K,
Dickenson AH, Wood JN. Deletion of annexin 2 light chain p11 in nociceptors
causes deficits in somatosensory coding and pain behavior. J Neurosci. 2006 Oct
11;26(41):10499-507. doi: 10.1523/JNEUROSCI.1997-06.2006. PMID: 17035534; PMCID:
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150: Suzuki R, Porreca F, Dickenson AH. Evidence for spinal dorsal horn
hyperexcitability in rats following sustained morphine exposure. Neurosci Lett.
2006 Oct 23;407(2):156-61. doi: 10.1016/j.neulet.2006.08.027. Epub 2006 Sep 7.
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151: Rygh LJ, Suzuki R, Rahman W, Wong Y, Vonsy JL, Sandhu H, Webber M, Hunt S,
Dickenson AH. Local and descending circuits regulate long-term potentiation and
zif268 expression in spinal neurons. Eur J Neurosci. 2006 Aug;24(3):761-72. doi:
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152: Li CY, Zhang XL, Matthews EA, Li KW, Kurwa A, Boroujerdi A, Gross J, Gold
MS, Dickenson AH, Feng G, Luo ZD. Calcium channel alpha2delta1 subunit mediates
spinal hyperexcitability in pain modulation. Pain. 2006 Nov;125(1-2):20-34. doi:
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153: Rahman W, Suzuki R, Webber M, Hunt SP, Dickenson AH. Depletion of
endogenous spinal 5-HT attenuates the behavioural hypersensitivity to mechanical
and cooling stimuli induced by spinal nerve ligation. Pain. 2006
Aug;123(3):264-74. doi: 10.1016/j.pain.2006.02.033. Epub 2006 Apr 27. PMID:
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154: Matthews EA, Wood JN, Dickenson AH. Na(v) 1.8-null mice show stimulus-
dependent deficits in spinal neuronal activity. Mol Pain. 2006 Feb 14;2:5. doi:
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155: Suzuki R, Dickenson AH. Differential pharmacological modulation of the
spontaneous stimulus-independent activity in the rat spinal cord following
peripheral nerve injury. Exp Neurol. 2006 Mar;198(1):72-80. doi:
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156: Dickenson AH, Bee LA, Suzuki R. Pains, gains, and midbrains. Proc Natl Acad
Sci U S A. 2005 Dec 13;102(50):17885-6. doi: 10.1073/pnas.0508494102. Epub 2005
Dec 5. PMID: 16330782; PMCID: PMC1312401.
157: Urch CE, Donovan-Rodriguez T, Gordon-Williams R, Bee LA, Dickenson AH.
Efficacy of chronic morphine in a rat model of cancer-induced bone pain:
behavior and in dorsal horn pathophysiology. J Pain. 2005 Dec;6(12):837-45. doi:
10.1016/j.jpain.2005.08.005. PMID: 16326372.
158: Donovan-Rodriguez T, Urch CE, Dickenson AH. Evidence of a role for
descending serotonergic facilitation in a rat model of cancer-induced bone pain.
Neurosci Lett. 2006 Jan 30;393(2-3):237-42. doi: 10.1016/j.neulet.2005.09.073.
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159: Suzuki R, Rahman W, Rygh LJ, Webber M, Hunt SP, Dickenson AH. Spinal-
supraspinal serotonergic circuits regulating neuropathic pain and its treatment
with gabapentin. Pain. 2005 Oct;117(3):292-303. doi: 10.1016/j.pain.2005.06.015.
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160: Dickenson AH, Carpenter K, Suzuki R. Pain relief. IDrugs. 1999
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161: Condés-Lara M, Maie IA, Dickenson AH. Oxytocin actions on afferent evoked
spinal cord neuronal activities in neuropathic but not in normal rats. Brain
Res. 2005 May 31;1045(1-2):124-33. doi: 10.1016/j.brainres.2005.03.020. Epub
2005 Apr 21. PMID: 15910770.
162: Bahia PK, Suzuki R, Benton DC, Jowett AJ, Chen MX, Trezise DJ, Dickenson
AH, Moss GW. A functional role for small-conductance calcium-activated potassium
channels in sensory pathways including nociceptive processes. J Neurosci. 2005
Apr 6;25(14):3489-98. doi: 10.1523/JNEUROSCI.0597-05.2005. PMID: 15814779;
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163: Dickenson AH, Suzuki R. Opioids in neuropathic pain: clues from animal
studies. Eur J Pain. 2005 Apr;9(2):113-6. doi: 10.1016/j.ejpain.2004.05.004.
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164: Hansson PT, Dickenson AH. Pharmacological treatment of peripheral
neuropathic pain conditions based on shared commonalities despite multiple
etiologies. Pain. 2005 Feb;113(3):251-4. doi: 10.1016/j.pain.2004.10.007. PMID:
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165: Stirling LC, Forlani G, Baker MD, Wood JN, Matthews EA, Dickenson AH,
Nassar MA. Nociceptor-specific gene deletion using heterozygous NaV1.8-Cre
recombinase mice. Pain. 2005 Jan;113(1-2):27-36. doi:
10.1016/j.pain.2004.08.015. PMID: 15621361.
166: Donovan-Rodriguez T, Dickenson AH, Urch CE. Gabapentin normalizes spinal
neuronal responses that correlate with behavior in a rat model of cancer-induced
bone pain. Anesthesiology. 2005 Jan;102(1):132-40. doi:
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167: Suzuki R, Rygh LJ, Dickenson AH. Bad news from the brain: descending 5-HT
pathways that control spinal pain processing. Trends Pharmacol Sci. 2004
Dec;25(12):613-7. doi: 10.1016/j.tips.2004.10.002. PMID: 15530638.
168: Nassar MA, Stirling LC, Forlani G, Baker MD, Matthews EA, Dickenson AH,
Wood JN. Nociceptor-specific gene deletion reveals a major role for Nav1.7 (PN1)
in acute and inflammatory pain. Proc Natl Acad Sci U S A. 2004 Aug
24;101(34):12706-11. doi: 10.1073/pnas.0404915101. Epub 2004 Aug 16. PMID:
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169: Suzuki R, Rahman W, Hunt SP, Dickenson AH. Descending facilitatory control
of mechanically evoked responses is enhanced in deep dorsal horn neurones
following peripheral nerve injury. Brain Res. 2004 Sep 3;1019(1-2):68-76. doi:
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170: Rahman W, Suzuki R, Rygh LJ, Dickenson AH. Descending serotonergic
facilitation mediated through rat spinal 5HT3 receptors is unaltered following
carrageenan inflammation. Neurosci Lett. 2004 May 6;361(1-3):229-31. doi:
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171: Stanfa LC, Dickenson AH. In vivo electrophysiology of dorsal-horn neurons.
Methods Mol Med. 2004;99:139-53. doi: 10.1007/978-1-59259-770-3_12. PMID:
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172: Seagrove LC, Suzuki R, Dickenson AH. Electrophysiological characterisations
of rat lamina I dorsal horn neurones and the involvement of excitatory amino
acid receptors. Pain. 2004 Mar;108(1-2):76-87. doi: 10.1016/j.pain.2003.12.004.
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173: Donovan-Rodriguez T, Dickenson AH, Urch CE. Superficial dorsal horn
neuronal responses and the emergence of behavioural hyperalgesia in a rat model
of cancer-induced bone pain. Neurosci Lett. 2004 Apr 22;360(1-2):29-32. doi:
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174: Matthews EA, Dickenson AH. Effects of spinally administered adenine on
dorsal horn neuronal responses in a rat model of inflammation. Neurosci Lett.
2004 Feb 19;356(3):211-4. doi: 10.1016/j.neulet.2003.11.057. PMID: 15036632.
175: Suzuki R, Edwards M, Dickenson AH. ReN-1869 [(R)-1-(3-(10,11-dihydro-5H-dib
enzo[a,d]cyclohepten-5-ylidene)-1-propyl)-3-piperidine carboxylic acid], a novel
histamine H1 receptor antagonist, produces potent and selective antinociceptive
effects on dorsal horn neurons after inflammation and neuropathy. J Pharmacol
Exp Ther. 2004 Jun;309(3):1230-8. doi: 10.1124/jpet.103.063511. Epub 2004 Feb
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176: Maie IA, Dickenson AH. Cholecystokinin fails to block the spinal inhibitory
effects of nociceptin in sham operated and neuropathic rats. Eur J Pharmacol.
2004 Jan 26;484(2-3):235-40. doi: 10.1016/j.ejphar.2003.11.030. PMID: 14744608.
177: Flatters SJ, Fox AJ, Dickenson AH. Nerve injury alters the effects of
interleukin-6 on nociceptive transmission in peripheral afferents. Eur J
Pharmacol. 2004 Jan 26;484(2-3):183-91. doi: 10.1016/j.ejphar.2003.11.013. PMID:
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178: Urch CE, Donovan-Rodriguez T, Dickenson AH. Alterations in dorsal horn
neurones in a rat model of cancer-induced bone pain. Pain. 2003
Dec;106(3):347-56. doi: 10.1016/j.pain.2003.08.002. PMID: 14659517.
179: Suzuki R, Green GM, Millan MJ, Dickenson AH. Electrophysiologic
characterization of the antinociceptive actions of S18616, a novel and potent
alpha 2-adrenoceptor agonist, after acute and persistent pain states. J Pain.
2002 Jun;3(3):234-43. doi: 10.1054/jpai.2002.123651. PMID: 14622778.
180: Suzuki R, Hunt SP, Dickenson AH. The coding of noxious mechanical and
thermal stimuli of deep dorsal horn neurones is attenuated in NK1 knockout mice.
Neuropharmacology. 2003 Dec;45(8):1093-100. doi: 10.1016/s0028-3908(03)00281-8.
PMID: 14614952.
181: Urch CE, Dickenson AH. Neuronal nitric oxide synthase modulation of dorsal
horn neuronal responses in the rat: a developmental study. Dev Neurosci. 2003
Sep-Oct;25(5):301-7. doi: 10.1159/000073506. PMID: 14614256.
182: Carpenter KJ, Sen S, Matthews EA, Flatters SL, Wozniak KM, Slusher BS,
Dickenson AH. Effects of GCP-II inhibition on responses of dorsal horn neurones
after inflammation and neuropathy: an electrophysiological study in the rat.
Neuropeptides. 2003 Oct;37(5):298-306. doi: 10.1016/j.npep.2003.08.001. PMID:
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183: McCleane GJ, Suzuki R, Dickenson AH. Does a single intravenous injection of
the 5HT3 receptor antagonist ondansetron have an analgesic effect in neuropathic
pain? A double-blinded, placebo-controlled cross-over study. Anesth Analg. 2003
Nov;97(5):1474-8. doi: 10.1213/01.ane.0000085640.69855.51. PMID: 14570668.
184: Flatters SJ, Fox AJ, Dickenson AH. Spinal interleukin-6 (IL-6) inhibits
nociceptive transmission following neuropathy. Brain Res. 2003 Sep
12;984(1-2):54-62. doi: 10.1016/s0006-8993(03)03092-0. PMID: 12932839.
185: Urch CE, Dickenson AH. In vivo single unit extracellular recordings from
spinal cord neurones of rats. Brain Res Brain Res Protoc. 2003 Aug;12(1):26-34.
doi: 10.1016/s1385-299x(03)00068-0. PMID: 12928042.
186: Passmore GM, Selyanko AA, Mistry M, Al-Qatari M, Marsh SJ, Matthews EA,
Dickenson AH, Brown TA, Burbidge SA, Main M, Brown DA. KCNQ/M currents in
sensory neurons: significance for pain therapy. J Neurosci. 2003 Aug
6;23(18):7227-36. doi: 10.1523/JNEUROSCI.23-18-07227.2003. PMID: 12904483;
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187: Flatters SJ, Fox AJ, Dickenson AH. In vivo and in vitro effects of
peripheral galanin on nociceptive transmission in naive and neuropathic states.
Neuroscience. 2003;116(4):1005-12. doi: 10.1016/s0306-4522(02)00947-8. PMID:
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188: Suzuki R, Morcuende S, Webber M, Hunt SP, Dickenson AH. Superficial
NK1-expressing neurons control spinal excitability through activation of
descending pathways. Nat Neurosci. 2002 Dec;5(12):1319-26. doi: 10.1038/nn966.
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189: Dickenson AH. Gate control theory of pain stands the test of time. Br J
Anaesth. 2002 Jun;88(6):755-7. doi: 10.1093/bja/88.6.755. PMID: 12173188.
190: Flatters SJ, Fox AJ, Dickenson AH. Nerve injury induces plasticity that
results in spinal inhibitory effects of galanin. Pain. 2002 Aug;98(3):249-58.
doi: 10.1016/s0304-3959(02)00180-x. Erratum in: Pain 2002 Oct;99(3):611-3. PMID:
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191: Suzuki R, Dickenson AH. Neuropharmacologic targets and agents in
fibromyalgia. Curr Pain Headache Rep. 2002 Aug;6(4):267-73. doi:
10.1007/s11916-002-0047-0. PMID: 12095461.
192: Carpenter KJ, Dickenson AH. Molecular aspects of pain research.
Pharmacogenomics J. 2002;2(2):87-95. doi: 10.1038/sj.tpj.6500095. PMID:
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193: Suzuki R, Dickenson AH. Nerve injury-induced changes in opioid modulation
of wide dynamic range dorsal column nuclei neurones. Neuroscience.
2002;111(1):215-28. doi: 10.1016/s0306-4522(01)00617-0. PMID: 11955724.
194: Dickenson AH, Matthews EA, Suzuki R. Neurobiology of neuropathic pain: mode
of action of anticonvulsants. Eur J Pain. 2002;6 Suppl A:51-60. doi:
10.1053/eujp.2001.0323. PMID: 11888242.
195: Matthews EA, Dickenson AH. A combination of gabapentin and morphine
mediates enhanced inhibitory effects on dorsal horn neuronal responses in a rat
model of neuropathy. Anesthesiology. 2002 Mar;96(3):633-40. doi:
10.1097/00000542-200203000-00020. PMID: 11873039.
196: Carpenter KJ, Dickenson AH. Amino acids are still as exciting as ever. Curr
Opin Pharmacol. 2001 Feb;1(1):57-61. doi: 10.1016/s1471-4892(01)00009-1. PMID:
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197: Matthews EA, Dickenson AH. Effects of spinally delivered N- and P-type
voltage-dependent calcium channel antagonists on dorsal horn neuronal responses
in a rat model of neuropathy. Pain. 2001 May;92(1-2):235-46. doi:
10.1016/s0304-3959(01)00255-x. PMID: 11323145.
198: Matthews EA, Dickenson AH. Effects of ethosuximide, a T-type Ca(2+) channel
blocker, on dorsal horn neuronal responses in rats. Eur J Pharmacol. 2001
Mar;415(2-3):141-9. doi: 10.1016/s0014-2999(01)00812-3. PMID: 11274992.
199: Suzuki R, Stanfa LC, Kowaluk EA, Williams M, Jarvis MF, Dickenson AH. The
effect of ABT-702, a novel adenosine kinase inhibitor, on the responses of
spinal neurones following carrageenan inflammation and peripheral nerve injury.
Br J Pharmacol. 2001 Apr;132(7):1615-23. doi: 10.1038/sj.bjp.0703972. PMID:
11264257; PMCID: PMC1572706.
200: Suzuki R, Matthews EA, Dickenson AH. Comparison of the effects of MK-801,
ketamine and memantine on responses of spinal dorsal horn neurones in a rat
model of mononeuropathy. Pain. 2001 Mar;91(1-2):101-9. doi:
10.1016/s0304-3959(00)00423-1. PMID: 11240082.
201: Kontinen VK, Stanfa LC, Basu A, Dickenson AH. Electrophysiologic evidence
for increased endogenous gabaergic but not glycinergic inhibitory tone in the
rat spinal nerve ligation model of neuropathy. Anesthesiology. 2001
Feb;94(2):333-9. doi: 10.1097/00000542-200102000-00024. PMID: 11176099.
202: Urch CE, Rahman W, Dickenson AH. Electrophysiological studies on the role
of the NMDA receptor in nociception in the developing rat spinal cord. Brain Res
Dev Brain Res. 2001 Jan 31;126(1):81-9. doi: 10.1016/s0165-3806(00)00141-3.
PMID: 11172889.
203: Carpenter KJ, Nandi M, Dickenson AH. Peripheral administration of low pH
solutions causes activation and sensitisation of convergent dorsal horn neurones
in the anaesthetised rat. Neurosci Lett. 2001 Feb 9;298(3):179-82. doi:
10.1016/s0304-3940(00)01759-6. PMID: 11165436.
204: Stanfa LC, Hampton DW, Dickenson AH. Role of Ca2+-permeable non-NMDA
glutamate receptors in spinal nociceptive transmission. Neuroreport. 2000 Sep
28;11(14):3199-202. doi: 10.1097/00001756-200009280-00030. PMID: 11043548.
205: Suzuki R, Dickenson AH. Neuropathic pain: nerves bursting with excitement
.. Neuroreport. 2000 Aug 21;11(12):R17-21. doi:
10.1097/00001756-200008210-00001. PMID: 10976929.
206: Rygh LJ, Kontinen VK, Suzuki R, Dickenson AH. Different increase in C-fibre
evoked responses after nociceptive conditioning stimulation in sham-operated and
neuropathic rats. Neurosci Lett. 2000 Jul 14;288(2):99-102. doi:
10.1016/s0304-3940(00)01201-5. PMID: 10876070.
207: Dickenson AH, Stanfa LC, Kontinen V, Suzuki R, Carpenter K. Comment on:
Svendsen et al; some problems with wind-up and its calculation, PAIN 83 (1999)
109-111. Pain. 2000 Apr;85(3):524. doi: 10.1016/s0304-3959(99)00291-2. PMID:
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208: Carpenter KJ, Chapman V, Dickenson AH. Neuronal inhibitory effects of
methadone are predominantly opioid receptor mediated in the rat spinal cord in
vivo. Eur J Pain. 2000;4(1):19-26. doi: 10.1053/eujp.1999.0147. PMID: 10833552.
209: Suzuki R, Kontinen VK, Matthews E, Williams E, Dickenson AH. Enlargement of
the receptive field size to low intensity mechanical stimulation in the rat
spinal nerve ligation model of neuropathy. Exp Neurol. 2000 Jun;163(2):408-13.
doi: 10.1006/exnr.2000.7371. PMID: 10833315.
210: Carpenter KJ, Vithlani M, Dickenson AH. Unaltered peripheral excitatory
actions of nociceptin contrast with enhanced spinal inhibitory effects after
carrageenan inflammation: an electrophysiological study in the rat. Pain. 2000
Apr;85(3):433-41. doi: 10.1016/s0304-3959(99)00301-2. PMID: 10781916.
211: Kontinen VK, Dickenson AH. Effects of midazolam in the spinal nerve
ligation model of neuropathic pain in rats. Pain. 2000 Apr;85(3):425-31. doi:
10.1016/s0304-3959(99)00298-5. PMID: 10781915.
212: Stanfa LC, Kontinen VK, Dickenson AH. Effects of spinally administered P2X
receptor agonists and antagonists on the responses of dorsal horn neurones
recorded in normal, carrageenan-inflamed and neuropathic rats. Br J Pharmacol.
2000 Jan;129(2):351-9. doi: 10.1038/sj.bjp.0703047. PMID: 10694242; PMCID:
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213: Rygh LJ, Green M, Athauda N, Tjølsen A, Dickenson AH. Effect of spinal
morphine after long-term potentiation of wide dynamic range neurones in the rat.
Anesthesiology. 2000 Jan;92(1):140-6. doi: 10.1097/00000542-200001000-00025.
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214: Carpenter KJ, Dickenson AH. NMDA receptors and pain--hopes for novel
analgesics. Reg Anesth Pain Med. 1999 Nov-Dec;24(6):506-8. doi:
10.1016/s1098-7339(99)90039-1. PMID: 10588552.
215: Stanfa LC, Dickenson AH. The role of non-N-methyl-D-aspartate ionotropic
glutamate receptors in the spinal transmission of nociception in normal animals
and animals with carrageenan inflammation. Neuroscience. 1999;93(4):1391-8. doi:
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216: Rahman W, Dickenson AH. Development of spinal opioid systems. Reg Anesth
Pain Med. 1999 Sep-Oct;24(5):383-5. doi: 10.1016/s1098-7339(99)90001-9. PMID:
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217: Chizh BA, Dickenson AH, Wnendt S. The race to control pain: more
participants, more targets. Trends Pharmacol Sci. 1999 Sep;20(9):354-7. doi:
10.1016/s0165-6147(99)01378-4. PMID: 10462755.
218: Akopian AN, Souslova V, England S, Okuse K, Ogata N, Ure J, Smith A, Kerr
BJ, McMahon SB, Boyce S, Hill R, Stanfa LC, Dickenson AH, Wood JN. The
tetrodotoxin-resistant sodium channel SNS has a specialized function in pain
pathways. Nat Neurosci. 1999 Jun;2(6):541-8. doi: 10.1038/9195. PMID: 10448219.
219: Rahman W, Dickenson AH. Electrophysiological studies on the postnatal
development of the spinal antinociceptive effects of the delta opioid receptor
agonist DPDPE in the rat. Br J Pharmacol. 1999 Mar;126(5):1115-22. doi:
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220: Suzuki R, Chapman V, Dickenson AH. The effectiveness of spinal and systemic
morphine on rat dorsal horn neuronal responses in the spinal nerve ligation
model of neuropathic pain. Pain. 1999 Mar;80(1-2):215-28. doi:
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221: Dickenson AH. Plasticity: implications for opioid and other pharmacological
interventions in specific pain states. Behav Brain Sci. 1997 Sep;20(3):392-403;
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222: Carpenter KJ, Dickenson AH. Evidence that [Phe1
psi(CH2-NH)Gly2]nociceptin-(1-13)-NH2, a peripheral ORL-1 receptor antagonist,
acts as an agonist in the rat spinal cord. Br J Pharmacol. 1998
Nov;125(5):949-51. doi: 10.1038/sj.bjp.0702188. PMID: 9846631; PMCID:
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223: Chapman V, Ng J, Dickenson AH. A novel spinal action of mexiletine in
spinal somatosensory transmission of nerve injured rats. Pain. 1998
Sep;77(3):289-96. doi: 10.1016/s0304-3959(98)00106-7. PMID: 9808354.
224: Rahman W, Dashwood MR, Fitzgerald M, Aynsley-Green A, Dickenson AH.
Postnatal development of multiple opioid receptors in the spinal cord and
development of spinal morphine analgesia. Brain Res Dev Brain Res. 1998 Jun
15;108(1-2):239-54. doi: 10.1016/s0165-3806(98)00054-6. PMID: 9693800.
225: Ebert B, Andersen S, Hjeds H, Dickenson AH. Dextropropoxyphene acts as a
noncompetitive N-methyl-D-aspartate antagonist. J Pain Symptom Manage. 1998
May;15(5):269-74. doi: 10.1016/s0885-3924(98)00015-3. PMID: 9654831.
226: Green GM, Lyons L, Dickenson AH. Alpha2-adrenoceptor antagonists enhance
responses of dorsal horn neurones to formalin induced inflammation. Eur J
Pharmacol. 1998 Apr 24;347(2-3):201-4. doi: 10.1016/s0014-2999(98)00217-9. PMID:
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227: Stanfa LC, Dickenson AH. Inflammation alters the effects of mGlu receptor
agonists on spinal nociceptive neurones. Eur J Pharmacol. 1998 Apr
24;347(2-3):165-72. doi: 10.1016/s0014-2999(98)00098-3. PMID: 9653877.
228: Chapman V, Suzuki R, Dickenson AH. Electrophysiological characterization of
spinal neuronal response properties in anaesthetized rats after ligation of
spinal nerves L5-L6. J Physiol. 1998 Mar 15;507 ( Pt 3)(Pt 3):881-94. doi:
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229: Chapman V, Suzuki R, Chamarette HL, Rygh LJ, Dickenson AH. Effects of
systemic carbamazepine and gabapentin on spinal neuronal responses in spinal
nerve ligated rats. Pain. 1998 Apr;75(2-3):261-72. doi:
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230: Reeve AJ, Dickenson AH, Kerr NC. Spinal effects of bicuculline: modulation
of an allodynia-like state by an A1-receptor agonist, morphine, and an NMDA-
receptor antagonist. J Neurophysiol. 1998 Mar;79(3):1494-507. doi:
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231: Bannon AW, Decker MW, Holladay MW, Curzon P, Donnelly-Roberts D,
Puttfarcken PS, Bitner RS, Diaz A, Dickenson AH, Porsolt RD, Williams M, Arneric
SP. Broad-spectrum, non-opioid analgesic activity by selective modulation of
neuronal nicotinic acetylcholine receptors. Science. 1998 Jan 2;279(5347):77-81.
doi: 10.1126/science.279.5347.77. PMID: 9417028.
232: Chapman V, Diaz A, Dickenson AH. Distinct inhibitory effects of spinal
endomorphin-1 and endomorphin-2 on evoked dorsal horn neuronal responses in the
rat. Br J Pharmacol. 1997 Dec;122(8):1537-9. doi: 10.1038/sj.bjp.0701594. PMID:
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233: Diaz A, Mayet S, Dickenson AH. BU-224 produces spinal antinociception as an
agonist at imidazoline I2 receptors. Eur J Pharmacol. 1997 Aug 20;333(1):9-15.
doi: 10.1016/s0014-2999(97)01118-7. PMID: 9311655.
234: Chapman V, Wildman MA, Dickenson AH. Distinct electrophysiological effects
of two spinally administered membrane stabilising drugs, bupivacaine and
lamotrigine. Pain. 1997 Jul;71(3):285-95. doi: 10.1016/s0304-3959(97)03365-4.
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235: Dickenson AH, Chapman V, Green GM. The pharmacology of excitatory and
inhibitory amino acid-mediated events in the transmission and modulation of pain
in the spinal cord. Gen Pharmacol. 1997 May;28(5):633-8. doi:
10.1016/s0306-3623(96)00359-x. PMID: 9184794.
236: Chapman V, Dickenson AH. Inflammation reveals inhibition of noxious
responses of rat spinal neurones by carbamazepine. Neuroreport. 1997 Apr
14;8(6):1399-404. doi: 10.1097/00001756-199704140-00016. PMID: 9172143.
237: Stanfa LC, Singh L, Williams RG, Dickenson AH. Gabapentin, ineffective in
normal rats, markedly reduces C-fibre evoked responses after inflammation.
Neuroreport. 1997 Feb 10;8(3):587-90. doi: 10.1097/00001756-199702100-00002.
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238: Dickenson AH. NMDA receptor antagonists: interactions with opioids. Acta
Anaesthesiol Scand. 1997 Jan;41(1 Pt 2):112-5. doi:
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239: Diaz A, Dickenson AH. Blockade of spinal N- and P-type, but not L-type,
calcium channels inhibits the excitability of rat dorsal horn neurones produced
by subcutaneous formalin inflammation. Pain. 1997 Jan;69(1-2):93-100. doi:
10.1016/s0304-3959(96)03271-x. PMID: 9060018.
240: Stanfa LC, Misra C, Dickenson AH. Amplification of spinal nociceptive
transmission depends on the generation of nitric oxide in normal and carrageenan
rats. Brain Res. 1996 Oct 21;737(1-2):92-8. doi: 10.1016/0006-8993(96)00629-4.
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241: Andersen S, Dickenson AH, Kohn M, Reeve A, Rahman W, Ebert B. The opioid
ketobemidone has a NMDA blocking effect. Pain. 1996 Oct;67(2-3):369-74. doi:
10.1016/0304-3959(96)03123-5. PMID: 8951931.
242: Boxall SJ, Thompson SW, Dray A, Dickenson AH, Urban L. Metabotropic
glutamate receptor activation contributes to nociceptive reflex activity in the
rat spinal cord in vitro. Neuroscience. 1996 Sep;74(1):13-20. doi:
10.1016/0306-4522(96)00101-7. PMID: 8843073.
243: Stanfa LC, Chapman V, Kerr N, Dickenson AH. Inhibitory action of nociceptin
on spinal dorsal horn neurones of the rat, in vivo. Br J Pharmacol. 1996
Aug;118(8):1875-7. doi: 10.1111/j.1476-5381.1996.tb15618.x. PMID: 8864517;
PMCID: PMC1909884.
244: Dickenson AH. Balances between excitatory and inhibitory events in the
spinal cord and chronic pain. Prog Brain Res. 1996;110:225-31. doi:
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245: Dickenson AH. Opioid receptors: electrophysiological and neurophysiological
approaches. Acta Anaesthesiol Belg. 1996;47(3):101-4. PMID: 8959193.
246: Chapman V, Dickenson AH. Time-related roles of excitatory amino acid
receptors during persistent noxiously evoked responses of rat dorsal horn
neurones. Brain Res. 1995 Dec 12;703(1-2):45-50. doi:
10.1016/0006-8993(95)01063-7. PMID: 8719614.
247: Reeve AJ, Dickenson AH. The roles of spinal adenosine receptors in the
control of acute and more persistent nociceptive responses of dorsal horn
neurones in the anaesthetized rat. Br J Pharmacol. 1995 Oct;116(4):2221-8. doi:
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248: Dickenson AH. Spinal cord pharmacology of pain. Br J Anaesth. 1995
Aug;75(2):193-200. doi: 10.1093/bja/75.2.193. PMID: 7577253.
249: Reeve AJ, Dickenson AH. Electrophysiological study on spinal
antinociceptive interactions between adenosine and morphine in the dorsal horn
of the rat. Neurosci Lett. 1995 Jul 14;194(1-2):81-4. doi:
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250: Dickenson AH. Central acute pain mechanisms. Ann Med. 1995 Apr;27(2):223-7.
doi: 10.3109/07853899509031963. PMID: 7632418.
251: Chapman V, Haley JE, Dickenson AH. Electrophysiologic analysis of
preemptive effects of spinal opioids on N-methyl-D-aspartate receptor-mediated
events. Anesthesiology. 1994 Dec;81(6):1429-35. doi:
10.1097/00000542-199412000-00018. PMID: 7992912.
252: Dickenson AH. O lokalizatsii i mekhanizmakh deĭstviia opioidov [The
localization and mechanisms of action of opioids]. Eksp Klin Farmakol. 1994 Nov-
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253: Sullivan AF, Hewett K, Dickenson AH. Differential modulation of alpha
2-adrenergic and opioid spinal antinociception by cholecystokinin and
cholecystokinin antagonists in the rat dorsal horn: an electrophysiological
study. Brain Res. 1994 Oct 31;662(1-2):141-7. doi: 10.1016/0006-8993(94)90806-0.
PMID: 7859067.
254: Chapman V, Dickenson AH, Tjølsen A. Bi-directional effects of intrathecal
NMDA and substance P on rat dorsal horn neuronal responses. Neurosci Lett. 1994
Aug 29;178(1):90-4. doi: 10.1016/0304-3940(94)90297-6. PMID: 7529389.
255: Chapman V, Dickenson AH. Enhanced responses of rat dorsal horn neurons
after UV irradiation of the hindpaw; roles of the NMDA receptor. Neurosci Lett.
1994 Jul 18;176(1):41-4. doi: 10.1016/0304-3940(94)90866-4. PMID: 7970233.
256: Devillers JP, Mazarguil H, Allard M, Dickenson AH, Zajac JM, Simonnet G.
Characterization of a potent agonist for NPFF receptors: binding study on rat
spinal cord membranes. Neuropharmacology. 1994 May;33(5):661-9. doi:
10.1016/0028-3908(94)90172-4. PMID: 7936102.
257: Stanfa LC, Dickenson AH. Electrophysiological studies on the spinal roles
of endogenous opioids in carrageenan inflammation. Pain. 1994 Feb;56(2):185-91.
doi: 10.1016/0304-3959(94)90093-0. PMID: 7911987.
258: Stanfa LC, Dickenson AH. Enhanced alpha-2 adrenergic controls and spinal
morphine potency in inflammation. Neuroreport. 1994 Jan 12;5(4):469-72. doi:
10.1097/00001756-199401120-00025. PMID: 8003677.
259: Dickenson AH. Neurophysiology of opioid poorly responsive pain. Cancer
Surv. 1994;21:5-16. PMID: 8564999.
260: Chapman V, Dickenson AH. The effect of intrathecal administration of
RP67580, a potent neurokinin 1 antagonist on nociceptive transmission in the rat
spinal cord. Neurosci Lett. 1993 Jul 23;157(2):149-52. doi:
10.1016/0304-3940(93)90724-y. PMID: 8233046.
261: Kalso EA, Sullivan AF, McQuay HJ, Dickenson AH, Roques BP. Cross-tolerance
between mu opioid and alpha-2 adrenergic receptors, but not between mu and delta
opioid receptors in the spinal cord of the rat. J Pharmacol Exp Ther. 1993
May;265(2):551-8. PMID: 8098759.
262: Stanfa LC, Dickenson AH. Cholecystokinin as a factor in the enhanced
potency of spinal morphine following carrageenin inflammation. Br J Pharmacol.
1993 Apr;108(4):967-73. doi: 10.1111/j.1476-5381.1993.tb13493.x. PMID: 8485635;
PMCID: PMC1908163.
263: Hewett K, Dickenson AH, McQuay HJ. Lack of effect of morphine-3-glucuronide
on the spinal antinociceptive actions of morphine in the rat: an
electrophysiological study. Pain. 1993 Apr;53(1):59-63. doi:
10.1016/0304-3959(93)90056-u. PMID: 8316391.
264: Chapman V, Dickenson AH. The effects of sandostatin and somatostatin on
nociceptive transmission in the dorsal horn of the rat spinal cord.
Neuropeptides. 1992 Nov;23(3):147-52. doi: 10.1016/0143-4179(92)90115-d. PMID:
1361670.
265: Chapman V, Dickenson AH. The spinal and peripheral roles of bradykinin and
prostaglandins in nociceptive processing in the rat. Eur J Pharmacol. 1992 Sep
4;219(3):427-33. doi: 10.1016/0014-2999(92)90484-l. PMID: 1425970.
266: Stanfa LC, Sullivan AF, Dickenson AH. Alterations in neuronal excitability
and the potency of spinal mu, delta and kappa opioids after carrageenan-induced
inflammation. Pain. 1992 Sep;50(3):345-54. doi: 10.1016/0304-3959(92)90040-i.
PMID: 1280804.
267: Kalso EA, Sullivan AF, McQuay HJ, Dickenson AH. Spinal antinociception by
Tyr-D-Ser(otbu)-Gly-Phe-Leu-Thr, a selective delta-opioid receptor agonist. Eur
J Pharmacol. 1992 May 27;216(1):97-101. doi: 10.1016/0014-2999(92)90214-o. PMID:
1326441.
268: Sullivan AF, Kalso EA, McQuay HJ, Dickenson AH. Evidence for the
involvement of the mu but not delta opioid receptor subtype in the synergistic
interaction between opioid and alpha 2 adrenergic antinociception in the rat
spinal cord. Neurosci Lett. 1992 May 11;139(1):65-8. doi:
10.1016/0304-3940(92)90859-6. PMID: 1357605.
269: Sullivan AF, Kalso EA, McQuay HJ, Dickenson AH. The antinociceptive actions
of dexmedetomidine on dorsal horn neuronal responses in the anaesthetized rat.
Eur J Pharmacol. 1992 Apr 29;215(1):127-33. doi: 10.1016/0014-2999(92)90617-d.
PMID: 1355441.
270: Fraser HM, Chapman V, Dickenson AH. Spinal local anaesthetic actions on
afferent evoked responses and wind-up of nociceptive neurones in the rat spinal
cord: combination with morphine produces marked potentiation of antinociception.
Pain. 1992 Apr;49(1):33-41. doi: 10.1016/0304-3959(92)90185-e. PMID: 1594281.
271: Haley JE, Dickenson AH, Schachter M. Electrophysiological evidence for a
role of nitric oxide in prolonged chemical nociception in the rat.
Neuropharmacology. 1992 Mar;31(3):251-8. doi: 10.1016/0028-3908(92)90175-o.
PMID: 1630593.
272: Chapman V, Dickenson AH. The combination of NMDA antagonism and morphine
produces profound antinociception in the rat dorsal horn. Brain Res. 1992 Feb
28;573(2):321-3. doi: 10.1016/0006-8993(92)90780-d. PMID: 1387029.
273: Kalliomäki J, Schouenborg J, Dickenson AH. Differential Effects of a
Distant Noxious Stimulus on Hindlimb Nociceptive Withdrawal Reflexes in the Rat.
Eur J Neurosci. 1992;4(7):648-652. doi: 10.1111/j.1460-9568.1992.tb00173.x.
PMID: 12106328.
274: Magnuson DS, Dickenson AH. Lamina-specific effects of morphine and naloxone
in dorsal horn of rat spinal cord in vitro. J Neurophysiol. 1991
Dec;66(6):1941-50. doi: 10.1152/jn.1991.66.6.1941. PMID: 1812227.
275: Dickenson AH, Dray A. Selective antagonism of capsaicin by capsazepine:
evidence for a spinal receptor site in capsaicin-induced antinociception. Br J
Pharmacol. 1991 Dec;104(4):1045-9. doi: 10.1111/j.1476-5381.1991.tb12547.x.
PMID: 1810591; PMCID: PMC1908854.
276: Dickenson AH, Sullivan AF, Stanfa LC, McQuay HJ. Dextromethorphan and
levorphanol on dorsal horn nociceptive neurones in the rat. Neuropharmacology.
1991 Dec;30(12A):1303-8. doi: 10.1016/0028-3908(91)90027-9. PMID: 1787884.
277: Sullivan AF, Kalso EA, McQuay HJ, Dickenson AH. FLFQPQRF-amide modulates
alpha 2-adrenergic antinociception in the rat dorsal horn in vivo. Brain Res.
1991 Oct 25;562(2):327-8. doi: 10.1016/0006-8993(91)90640-h. PMID: 1685347.
278: Dickenson AH, Sullivan AF. NMDA receptors and central hyperalgesic states.
Pain. 1991 Sep;46(3):344-6. doi: 10.1016/0304-3959(91)90118-h. PMID: 1836867.
279: Dickenson AH. Capsaicin: gaps in our knowledge start to be filled. Trends
Neurosci. 1991 Jul;14(7):265-6. doi: 10.1016/0166-2236(91)90133-f. PMID:
1719669.
280: Dickenson AH. Mechanisms of the analgesic actions of opiates and opioids.
Br Med Bull. 1991 Jul;47(3):690-702. doi: 10.1093/oxfordjournals.bmb.a072501.
PMID: 1665377.
281: Sullivan AF, Dickenson AH. Electrophysiologic studies on the spinal
antinociceptive action of kappa opioid agonists in the adult and 21-day-old rat.
J Pharmacol Exp Ther. 1991 Mar;256(3):1119-25. PMID: 2005577.
282: Dickenson AH, Aydar E. Antagonism at the glycine site on the NMDA receptor
reduces spinal nociception in the rat. Neurosci Lett. 1991 Jan 2;121(1-2):263-6.
doi: 10.1016/0304-3940(91)90700-4. PMID: 1826945.
283: Dickenson AH. Recent advances in the physiology and pharmacology of pain:
plasticity and its implications for clinical analgesia. J Psychopharmacol. 1991
Jan;5(4):342-51. doi: 10.1177/026988119100500424. PMID: 22282839.
284: Dickenson AH, Sullivan AF, McQuay HJ. Intrathecal etorphine, fentanyl and
buprenorphine on spinal nociceptive neurones in the rat. Pain. 1990
Aug;42(2):227-34. doi: 10.1016/0304-3959(90)91166-g. PMID: 2247319.
285: Magnuson DS, Sullivan AF, Simonnet G, Roques BP, Dickenson AH. Differential
interactions of cholecystokinin and FLFQPQRF-NH2 with mu and delta opioid
antinociception in the rat spinal cord. Neuropeptides. 1990 Aug;16(4):213-8.
doi: 10.1016/0143-4179(90)90065-7. PMID: 2177165.
286: Dickenson AH. A cure for wind up: NMDA receptor antagonists as potential
analgesics. Trends Pharmacol Sci. 1990 Aug;11(8):307-9. doi:
10.1016/0165-6147(90)90228-z. PMID: 2168102.
287: Haley JE, Sullivan AF, Dickenson AH. Evidence for spinal N-methyl-D-
aspartate receptor involvement in prolonged chemical nociception in the rat.
Brain Res. 1990 Jun 4;518(1-2):218-26. doi: 10.1016/0006-8993(90)90975-h. PMID:
1975214.
288: McQuay HJ, Dickenson AH. Implications of nervous system plasticity for pain
management. Anaesthesia. 1990 Feb;45(2):101-2. doi:
10.1111/j.1365-2044.1990.tb14270.x. PMID: 2157345.
289: Dickenson AH, Sullivan AF. Differential effects of excitatory amino acid
antagonists on dorsal horn nociceptive neurones in the rat. Brain Res. 1990 Jan
1;506(1):31-9. doi: 10.1016/0006-8993(90)91195-m. PMID: 1967963.
290: Poree LR, Dickenson AH, Wei ET. Corticotropin-releasing factor inhibits the
response of trigeminal neurons to noxious heat. Brain Res. 1989 Nov
20;502(2):349-55. doi: 10.1016/0006-8993(89)90631-8. PMID: 2819471.
291: Sullivan AF, Dickenson AH, Roques BP. Delta-opioid mediated inhibitions of
acute and prolonged noxious-evoked responses in rat dorsal horn neurones. Br J
Pharmacol. 1989 Nov;98(3):1039-49. doi: 10.1111/j.1476-5381.1989.tb14636.x.
PMID: 2556199; PMCID: PMC1854772.
292: Smallman K, Dickenson AH, Halsey MJ. Electrophysiological studies on the
effects of opiates on dorsal horn nociceptive neurones at 51 atmospheres
absolute. Pain. 1989 Jul;38(1):57-64. doi: 10.1016/0304-3959(89)90073-0. PMID:
2780064.
293: Sullivan AF, McQuay HJ, Bailey D, Dickenson AH. The spinal antinociceptive
actions of morphine metabolites morphine-6-glucuronide and normorphine in the
rat. Brain Res. 1989 Mar 20;482(2):219-24. doi: 10.1016/0006-8993(89)91184-0.
PMID: 2706485.
294: Haley JE, Dickenson AH, Schachter M. Electrophysiological evidence for a
role of bradykinin in chemical nociception in the rat. Neurosci Lett. 1989 Feb
13;97(1-2):198-202. doi: 10.1016/0304-3940(89)90163-8. PMID: 2537479.
295: McQuay HJ, Sullivan AF, Smallman K, Dickenson AH. Intrathecal opioids,
potency and lipophilicity. Pain. 1989 Jan;36(1):111-5. doi:
10.1016/0304-3959(89)90118-8. PMID: 2537486.
296: Sullivan AF, Dickenson AH. Electrophysiological studies on the spinal
effects of dermorphin, an endogenous mu-opioid agonist. Brain Res. 1988 Sep
27;461(1):182-5. doi: 10.1016/0006-8993(88)90738-x. PMID: 2906269.
297: Dickenson AH, Sullivan AF, Roques BP. Evidence that endogenous enkephalins
and a delta opioid receptor agonist have a common site of action in spinal
antinociception. Eur J Pharmacol. 1988 Apr 13;148(3):437-9. doi:
10.1016/0014-2999(88)90123-9. PMID: 2838307.
298: Zajac JM, Dauge V, Dickenson AH, Roques BP. Enképhalines et analgésie
[Enkephalins and analgesia]. Agressologie. 1988 Feb;29(2):67-70. French. PMID:
2841881.
299: Dickenson AH, Sullivan AF. Peripheral origins and central modulation of
subcutaneous formalin-induced activity of rat dorsal horn neurones. Neurosci
Lett. 1987 Dec 16;83(1-2):207-11. doi: 10.1016/0304-3940(87)90242-4. PMID:
3441298.
300: Dickenson AH, Le Bars D. Lack of evidence for increased descending
inhibition on the dorsal horn of the rat following periaqueductal grey morphine
microinjections. Br J Pharmacol. 1987 Oct;92(2):271-80. doi:
10.1111/j.1476-5381.1987.tb11321.x. PMID: 3676594; PMCID: PMC1853651.
301: Dickenson AH, Sullivan AF. Subcutaneous formalin-induced activity of dorsal
horn neurones in the rat: differential response to an intrathecal opiate
administered pre or post formalin. Pain. 1987 Sep;30(3):349-60. doi:
10.1016/0304-3959(87)90023-6. PMID: 3670880.
302: Dickenson AH, Sullivan AF. Evidence for a role of the NMDA receptor in the
frequency dependent potentiation of deep rat dorsal horn nociceptive neurones
following C fibre stimulation. Neuropharmacology. 1987 Aug;26(8):1235-8. doi:
10.1016/0028-3908(87)90275-9. PMID: 2821443.
303: Knox RJ, Dickenson AH. Effects of selective and non-selective kappa-opioid
receptor agonists on cutaneous C-fibre-evoked responses of rat dorsal horn
neurones. Brain Res. 1987 Jul 7;415(1):21-9. doi: 10.1016/0006-8993(87)90265-4.
PMID: 2887243.
304: Sullivan AF, Dashwood MR, Dickenson AH. Alpha 2-adrenoceptor modulation of
nociception in rat spinal cord: location, effects and interactions with
morphine. Eur J Pharmacol. 1987 Jun 19;138(2):169-77. doi:
10.1016/0014-2999(87)90430-4. PMID: 3040431.
305: Dickenson AH, Sullivan AF, Knox R, Zajac JM, Roques BP. Opioid receptor
subtypes in the rat spinal cord: electrophysiological studies with mu- and
delta-opioid receptor agonists in the control of nociception. Brain Res. 1987
Jun 9;413(1):36-44. doi: 10.1016/0006-8993(87)90151-x. PMID: 3036317.
306: Dickenson AH, Sullivan AF, Fournie-Zaluski MC, Roques BP. Prevention of
degradation of endogenous enkephalins produces inhibition of nociceptive
neurones in rat spinal cord. Brain Res. 1987 Apr 7;408(1-2):185-91. doi:
10.1016/0006-8993(87)90370-2. PMID: 3474047.
307: Dickenson AH, Knox RJ. Antagonism of mu-opioid receptor-mediated
inhibitions of nociceptive neurones by U50488H and dynorphin A1-13 in the rat
dorsal horn. Neurosci Lett. 1987 Mar 31;75(2):229-34. doi:
10.1016/0304-3940(87)90302-8. PMID: 2883617.
308: Dickenson AH, Le Bars D. Supraspinal morphine and descending inhibitions
acting on the dorsal horn of the rat. J Physiol. 1987 Mar;384:81-107. doi:
10.1113/jphysiol.1987.sp016444. PMID: 3309265; PMCID: PMC1192252.
309: Dickenson AH, Sullivan A, Feeney C, Fournie-Zaluski MC, Roques BP. Evidence
that endogenous enkephalins produce delta-opiate receptor mediated neuronal
inhibitions in rat dorsal horn. Neurosci Lett. 1986 Dec 12;72(2):179-82. doi:
10.1016/0304-3940(86)90076-5. PMID: 3027626.
310: Dickenson AH, Goldsmith G. Evidence for a role of 5-hydroxytryptamine in
the responses of rat raphe magnus neurones to peripheral noxious stimuli.
Neuropharmacology. 1986 Aug;25(8):863-8. doi: 10.1016/0028-3908(86)90012-2.
PMID: 3022179.
311: Dickenson AH. Enkephalins. A new approach to pain relief? Nature. 1986 Apr
24-30;320(6064):681-2. doi: 10.1038/320681a0. PMID: 3517655.
312: Dickenson AH, Sullivan AF. Electrophysiological studies on the effects of
intrathecal morphine on nociceptive neurones in the rat dorsal horn. Pain. 1986
Feb;24(2):211-22. doi: 10.1016/0304-3959(86)90044-8. PMID: 3754322.
313: Fournié-Zaluski MC, Bourgoin S, Cesselin F, Hamon M, Le Bars D, Dickenson
AH, Roques BP. Increase in met-enkephalin level and antinociceptive effects
induced by kelatorphan in the rat spinal cord. NIDA Res Monogr. 1986;75:454-6.
PMID: 3123963.
314: Dickenson AH, Brewer CM, Hayes NA. Effects of topical baclofen on C fibre-
evoked neuronal activity in the rat dorsal horn. Neuroscience. 1985
Feb;14(2):557-62. doi: 10.1016/0306-4522(85)90310-0. PMID: 2986041.
315: Dickenson AH, Le Bars D. Diffuse noxious inhibitory controls (DNIC) involve
trigeminothalamic and spinothalamic neurones in the rat. Exp Brain Res.
1983;49(2):174-80. doi: 10.1007/BF00238577. PMID: 6832255.
316: Dickenson AH, Le Bars D. Morphine microinjections into periaqueductal grey
matter of the rat: effects on dorsal horn neuronal responses to C-fibre activity
and diffuse noxious inhibitory controls. Life Sci. 1983;33 Suppl 1:549-52. doi:
10.1016/0024-3205(83)90562-3. PMID: 6664236.
317: Chitour D, Dickenson AH, Le Bars D. Pharmacological evidence for the
involvement of serotonergic mechanisms in diffuse noxious inhibitory controls
(DNIC). Brain Res. 1982 Mar 25;236(2):329-37. doi: 10.1016/0006-8993(82)90718-1.
PMID: 6978166.
318: Dickenson AH, Rivot JP, Chaouch A, Besson JM, Le Bars D. Diffuse noxious
inhibitory controls (DNIC) in the rat with or without pCPA pretreatment. Brain
Res. 1981 Jul 20;216(2):313-21. doi: 10.1016/0006-8993(81)90133-5. PMID:
6454457.
319: Dickenson AH, Le Bars D, Besson JM. Endogenous opiates and nociception: a
possible functional role in both pain inhibition and detection as revealed by
intrathecal naloxone. Neurosci Lett. 1981 Jul 2;24(2):161-4. doi:
10.1016/0304-3940(81)90241-x. PMID: 7254713.
320: Le Bars D, Chitour D, Kraus E, Clot AM, Dickenson AH, Besson JM. The effect
of systemic morphine upon diffuse noxious inhibitory controls (DNIC) in the rat:
evidence for a lifting of certain descending inhibitory controls of dorsal horn
convergent neurones. Brain Res. 1981 Jun 29;215(1-2):257-74. doi:
10.1016/0006-8993(81)90506-0. PMID: 7260590.
321: Dickenson AH, Hellon RF, Woolf CJ. Tooth pulp input to the spinal
trigeminal nucleus: a comparison of inhibitions following segmental and raphe
magnus stimulation. Brain Res. 1981 Jun 9;214(1):73-87. doi:
10.1016/0006-8993(81)90439-x. PMID: 7237167.
322: Dawson NJ, Dickenson AH, Hellon RF, Woolf CJ. Inhibitory controls on
thermal neurones in the spinal trigeminal nucleus of cats and rats. Brain Res.
1981 Mar 30;209(2):440-5. doi: 10.1016/0006-8993(81)90167-0. PMID: 7225804.
323: Le Bars D, Dickenson AH, Rivot JP, Chitour D, Chaouch A, Kraus E, Besson
JM. Les systèmes sérotoninergiques bulbo-spinaux jouent-ils un rôle dans la
détection des messages nociceptifs? [Are bulbo-spinal serotonergic systems
involved in the detection of nociceptive messages? (author's transl)]. J Physiol
(Paris). 1981;77(2-3):463-71. French. PMID: 6270318.
324: Dickenson AH, Le Bars D, Besson JM. Diffuse noxious inhibitory controls
(DNIC). Effects on trigeminal nucleus caudalis neurones in the rat. Brain Res.
1980 Nov 3;200(2):293-305. doi: 10.1016/0006-8993(80)90921-x. PMID: 7417817.
325: Le Bars D, Chitour D, Kraus E, Dickenson AH, Besson JM. Dépression par la
morphine de certains contrôles inhibiteurs descendants qui modulent, chez le
rat, la transmission des messages nociceptifs au niveau spinal [Depression by
morphine of various descending inhibitory controls modulating the transmission
of nociceptive information at the spinal level in the rat]. C R Seances Acad Sci
D. 1980 Sep 29;291(4):433-6. French. PMID: 6777065.
326: Le Bars D, Dickenson AH, Besson JM. Microinjection of morphine within
nucleus raphe magnus and dorsal horn neurone activities related to nociception
in the rat. Brain Res. 1980 May 12;189(2):467-81. doi:
10.1016/0006-8993(80)90106-7. PMID: 6245766.
327: Le Bars D, Rivot JP, Dickenson AH, Chaouch A, Besson JM. Rôle de la
sérontonine dans les contrôles inhibiteurs diffus induits par des stimulations
nociceptives [Role of serotonin in the diffuse inhibitory controls induced by
nociceptive stimulation]. C R Seances Acad Sci D. 1980 Jan 28;290(4):379-82.
French. PMID: 6444550.
328: Le Bars D, Chitour D, Kraus E, Dickenson AH, Besson JM. Effect of naloxone
upon diffuse noxious inhibitory controls (DNIC) in the rat. Brain Res. 1981 Jan
12;204(2):387-402. doi: 10.1016/0006-8993(81)90597-7. PMID: 6257327.
329: Dickenson AH, Fardin V, Le Bars D, Besson JM. Antinociceptive action
following microinjection of methionine-enkephalin in the nucleus raphe magnus of
the rat. Neurosci Lett. 1979 Dec;15(2-3):265-70. doi:
10.1016/0304-3940(79)96124-x. PMID: 530531.
330: Dickenson AH, Oliveras JL, Besson JM. Role of the nucleus raphe magnus in
opiate analgesia as studied by the microinjection technique in the rat. Brain
Res. 1979 Jul 6;170(1):95-111. doi: 10.1016/0006-8993(79)90943-0. PMID: 223722.
331: Besson JM, Dickenson AH, Le Bars D. Plurisegmental noxious inhibitory
controls on rat dorsal horn convergent neurones [proceedings]. J Physiol. 1979
Jul;292:41P-42P. PMID: 490372.
332: Le Bars D, Dickenson AH, Besson JM. Diffuse noxious inhibitory controls
(DNIC). II. Lack of effect on non-convergent neurones, supraspinal involvement
and theoretical implications. Pain. 1979 Jun;6(3):305-27. doi:
10.1016/0304-3959(79)90050-2. PMID: 460936.
333: Le Bars D, Dickenson AH, Besson JM. Diffuse noxious inhibitory controls
(DNIC). I. Effects on dorsal horn convergent neurones in the rat. Pain. 1979
Jun;6(3):283-304. doi: 10.1016/0304-3959(79)90049-6. PMID: 460935.
334: Dickenson AH, Hellon RF, Taylor DC. Facial thermal input to the trigeminal
spinal nucleus of rabbits and rats. J Comp Neurol. 1979 May 1;185(1):203-9. doi:
10.1002/cne.901850112. PMID: 429614.
335: Dickenson AH, Oliveras JL, Besson JM. Rôle du noyau Raphé Magnus dans
l'analgésie morphinique : Etudes par microinjections intracérébrales chez le rat
[Role of the Raphe Magnus nucleus in morphine analgesia : studies with
intracerebral microinjections in the rat]. C R Acad Hebd Seances Acad Sci D.
1978 Oct 23;287(10):955-8. French. PMID: 106979.
336: Dickenson AH. Specific responses of rat raphé neurones to skin temperature.
J Physiol. 1977 Dec;273(1):277-93. doi: 10.1113/jphysiol.1977.sp012094. PMID:
599422; PMCID: PMC1353739.
337: Deakin JF, Dickenson AH, Dostrovsky JO. Morphine effects on rat raphé
magnus neurones [proceedings]. J Physiol. 1977 May;267(1):43P-45P. PMID: 559757.
Plasticity of Descending Modulatory Controls in a Rodent Model of Cancer-Induced
Bone Pain. Cancers (Basel). 2020 Nov 6;12(11):3286. doi:
10.3390/cancers12113286. PMID: 33172040; PMCID: PMC7716240.
2: Kucharczyk MW, Chisholm KI, Denk F, Dickenson AH, Bannister K, McMahon SB.
The impact of bone cancer on the peripheral encoding of mechanical pressure
stimuli. Pain. 2020 Aug;161(8):1894-1905. doi: 10.1097/j.pain.0000000000001880.
PMID: 32701848; PMCID: PMC7365668.
3: Bannister K, Dickenson AH. Central Nervous System Targets: Supraspinal
Mechanisms of Analgesia. Neurotherapeutics. 2020 Jul;17(3):839-845. doi:
10.1007/s13311-020-00887-6. PMID: 32700132; PMCID: PMC7609795.
4: Bonezzi C, Costantini A, Cruccu G, Fornasari DMM, Guardamagna V, Palmieri V,
Polati E, Zini P, Dickenson AH. Capsaicin 8% dermal patch in clinical practice:
an expert opinion. Expert Opin Pharmacother. 2020 Aug;21(11):1377-1387. doi:
10.1080/14656566.2020.1759550. Epub 2020 Jun 8. PMID: 32511032.
5: Kucharczyk MW, Chisholm KI, Denk F, Dickenson AH, Bannister K, McMahon SB.
The impact of bone cancer on the peripheral encoding of mechanical pressure
stimuli. Pain. 2020 Apr 13. doi: 10.1097/j.pain.0000000000001880. Epub ahead of
print. PMID: 32301838.
6: Dickenson AH, Patel R. Translational issues in precision medicine in
neuropathic pain. Can J Pain. 2020 Jan 23;4(1):30-38. doi:
10.1080/24740527.2020.1720502. PMID: 32258972; PMCID: PMC7077367.
7: Caraci F, Coluzzi F, Marinangeli F, Mercadante S, Rinonapoli G, Romualdi P,
Nicora M, Dickenson AH. Modulation of sensitization processes in the management
of pain and the importance of descending pathways: a role for tapentadol? Curr
Med Res Opin. 2020 Jun;36(6):1015-1024. doi: 10.1080/03007995.2020.1748876. Epub
2020 Apr 9. PMID: 32216591.
8: Yosten GL, Harada CM, Haddock C, Giancotti LA, Kolar GR, Patel R, Guo C, Chen
Z, Zhang J, Doyle TM, Dickenson AH, Samson WK, Salvemini D. GPR160 de-
orphanization reveals critical roles in neuropathic pain in rodents. J Clin
Invest. 2020 May 1;130(5):2587-2592. doi: 10.1172/JCI133270. PMID: 31999650;
PMCID: PMC7190928.
9: Dickenson AH, Navratilova E, Patel R, Porreca F, Bannister K. Supraspinal
Opioid Circuits Differentially Modulate Spinal Neuronal Responses in Neuropathic
Rats. Anesthesiology. 2020 Apr;132(4):881-894. doi:
10.1097/ALN.0000000000003120. PMID: 31977518.
10: Bannister K, Sachau J, Baron R, Dickenson AH. Neuropathic Pain: Mechanism-
Based Therapeutics. Annu Rev Pharmacol Toxicol. 2020 Jan 6;60:257-274. doi:
10.1146/annurev-pharmtox-010818-021524. PMID: 31914896.
11: Caraci F, Coluzzi F, Marinangeli F, Mercadante S, Rinonapoli G, Romualdi P,
Nicora M, Dickenson AH. Modulation of sensitization processes in the management
of pain and the importance of descending pathways: a role for tapentadol? Curr
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12: Navratilova E, Nation K, Remeniuk B, Neugebauer V, Bannister K, Dickenson
AH, Porreca F. Selective modulation of tonic aversive qualities of neuropathic
pain by morphine in the central nucleus of the amygdala requires endogenous
opioid signaling in the anterior cingulate cortex. Pain. 2020
Mar;161(3):609-618. doi: 10.1097/j.pain.0000000000001748. PMID: 31725062; PMCID:
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13: Patel R, Dickenson AH. A study of cortical and brainstem mechanisms of
diffuse noxious inhibitory controls in anaesthetised normal and neuropathic
rats. Eur J Neurosci. 2020 Feb;51(4):952-962. doi: 10.1111/ejn.14576. Epub 2019
Oct 6. PMID: 31518451; PMCID: PMC7079135.
14: Lockwood S, Dickenson AH. What goes up must come down: insights from studies
on descending controls acting on spinal pain processing. J Neural Transm
(Vienna). 2020 Apr;127(4):541-549. doi: 10.1007/s00702-019-02077-x. Epub 2019
Sep 12. PMID: 31515656; PMCID: PMC7148257.
15: Carcolé M, Kummer S, Gonçalves L, Zamanillo D, Merlos M, Dickenson AH,
Fernández-Pastor B, Cabañero D, Maldonado R. Sigma-1 receptor modulates
neuroinflammation associated with mechanical hypersensitivity and opioid
tolerance in a mouse model of osteoarthritis pain. Br J Pharmacol. 2019
Oct;176(20):3939-3955. doi: 10.1111/bph.14794. Epub 2019 Sep 12. PMID: 31332781;
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16: Romualdi P, Grilli M, Canonico PL, Collino M, Dickenson AH. Pharmacological
rationale for tapentadol therapy: a review of new evidence. J Pain Res. 2019 May
16;12:1513-1520. doi: 10.2147/JPR.S190160. PMID: 31190962; PMCID: PMC6526917.
17: Dickenson AH, Kress HG. Tapentadol: a new option for the treatment of cancer
and noncancer pains. J Pain Res. 2019 May 16;12:1509-1511. doi:
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18: David-Pereira A, Dickenson AH. Issues in the future development of new
analgesic drugs. Curr Opin Support Palliat Care. 2019 Jun;13(2):107-110. doi:
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19: Phelps CE, Navratilova E, Dickenson AH, Porreca F, Bannister K. Kappa opioid
signaling in the right central amygdala causes hind paw specific loss of diffuse
noxious inhibitory controls in experimental neuropathic pain. Pain. 2019
Jul;160(7):1614-1621. doi: 10.1097/j.pain.0000000000001553. PMID: 30870321.
20: Lockwood SM, Dickenson AH. A combination pharmacotherapy of tapentadol and
pregabalin to tackle centrally driven osteoarthritis pain. Eur J Pain. 2019
Jul;23(6):1185-1195. doi: 10.1002/ejp.1386. Epub 2019 Mar 22. PMID: 30821870;
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21: Martínez-Navarro M, Lara-Mayorga IM, Negrete R, Bilecki W, Wawrzczak-
Bargieła A, Gonçalves L, Dickenson AH, Przewłocki R, Baños JE, Maldonado R.
Influence of behavioral traits in the inter-individual variability of
nociceptive, emotional and cognitive manifestations of neuropathic pain.
Neuropharmacology. 2019 Apr;148:291-304. doi: 10.1016/j.neuropharm.2019.01.012.
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22: Lockwood SM, Lopes DM, McMahon SB, Dickenson AH. Characterisation of
peripheral and central components of the rat monoiodoacetate model of
Osteoarthritis. Osteoarthritis Cartilage. 2019 Apr;27(4):712-722. doi:
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23: Lockwood SM, Bannister K, Dickenson AH. An investigation into the
noradrenergic and serotonergic contributions of diffuse noxious inhibitory
controls in a monoiodoacetate model of osteoarthritis. J Neurophysiol. 2019 Jan
1;121(1):96-104. doi: 10.1152/jn.00613.2018. Epub 2018 Nov 21. PMID: 30461363;
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24: Patel R, Dickenson AH. Modality selective roles of pro-nociceptive spinal
5-HT<sub>2A</sub> and 5-HT<sub>3</sub> receptors in normal and neuropathic
states. Neuropharmacology. 2018 Dec;143:29-37. doi:
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25: Patel R, Kucharczyk M, Montagut-Bordas C, Lockwood S, Dickenson AH.
Neuropathy following spinal nerve injury shares features with the irritable
nociceptor phenotype: A back-translational study of oxcarbazepine. Eur J Pain.
2019 Jan;23(1):183-197. doi: 10.1002/ejp.1300. Epub 2018 Aug 28. PMID: 30091265;
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26: Gomtsian L, Bannister K, Eyde N, Robles D, Dickenson AH, Porreca F,
Navratilova E. Morphine effects within the rodent anterior cingulate cortex and
rostral ventromedial medulla reveal separable modulation of affective and
sensory qualities of acute or chronic pain. Pain. 2018 Dec;159(12):2512-2521.
doi: 10.1097/j.pain.0000000000001355. PMID: 30086115; PMCID: PMC6320264.
27: Dickenson AH, Patel R. Sense and sensibility-logical approaches to profiling
in animal models. Pain. 2018 Jul;159(7):1426-1428. doi:
10.1097/j.pain.0000000000001245. PMID: 29916961; PMCID: PMC6027960.
28: Patel R, Qu C, Xie JY, Porreca F, Dickenson AH. Selective deficiencies in
descending inhibitory modulation in neuropathic rats: implications for enhancing
noradrenergic tone. Pain. 2018 Sep;159(9):1887-1899. doi:
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29: Dickenson AH, Farquhar-Smith P. Editorial for Pain: Cancer in 2018. Curr
Opin Support Palliat Care. 2018 Jun;12(2):101. doi:
10.1097/SPC.0000000000000344. PMID: 29608466.
30: Dickenson AH, Bannister K. Editorial for Pain: Nonmalignant Diseases in
2018. Curr Opin Support Palliat Care. 2018 Jun;12(2):131. doi:
10.1097/SPC.0000000000000343. PMID: 29608465.
31: Dawes JM, Weir GA, Middleton SJ, Patel R, Chisholm KI, Pettingill P, Peck
LJ, Sheridan J, Shakir A, Jacobson L, Gutierrez-Mecinas M, Galino J, Walcher J,
Kühnemund J, Kuehn H, Sanna MD, Lang B, Clark AJ, Themistocleous AC, Iwagaki N,
West SJ, Werynska K, Carroll L, Trendafilova T, Menassa DA, Giannoccaro MP,
Coutinho E, Cervellini I, Tewari D, Buckley C, Leite MI, Wildner H, Zeilhofer
HU, Peles E, Todd AJ, McMahon SB, Dickenson AH, Lewin GR, Vincent A, Bennett DL.
Immune or Genetic-Mediated Disruption of CASPR2 Causes Pain Hypersensitivity Due
to Enhanced Primary Afferent Excitability. Neuron. 2018 Feb
21;97(4):806-822.e10. doi: 10.1016/j.neuron.2018.01.033. Epub 2018 Feb 8. PMID:
29429934; PMCID: PMC6011627.
32: Dalmolin GD, Bannister K, Gonçalves L, Sikandar S, Patel R, Cordeiro MDN,
Gomez MV, Ferreira J, Dickenson AH. Effect of the spider toxin Tx3-3 on spinal
processing of sensory information in naive and neuropathic rats: an in vivo
electrophysiological study. Pain Rep. 2017 Jul 6;2(4):e610. doi:
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33: Dickenson AH. Holding down the pain. Brain. 2018 Jan 1;141(1):5-6. doi:
10.1093/brain/awx334. PMID: 29325048; PMCID: PMC5837699.
34: Bannister K, Qu C, Navratilova E, Oyarzo J, Xie JY, King T, Dickenson AH,
Porreca F. Multiple sites and actions of gabapentin-induced relief of ongoing
experimental neuropathic pain. Pain. 2017 Dec;158(12):2386-2395. doi:
10.1097/j.pain.0000000000001040. PMID: 28832395; PMCID: PMC5681862.
35: Sikandar S, West SJ, McMahon SB, Bennett DL, Dickenson AH. Sensory
processing of deep tissue nociception in the rat spinal cord and thalamic
ventrobasal complex. Physiol Rep. 2017 Jul;5(14):e13323. doi:
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36: Bannister K, Kucharczyk M, Dickenson AH. Hopes for the Future of Pain
Control. Pain Ther. 2017 Dec;6(2):117-128. doi: 10.1007/s40122-017-0073-6. Epub
2017 May 23. PMID: 28536900; PMCID: PMC5693804.
37: Bannister K, Dickenson AH. The plasticity of descending controls in pain:
translational probing. J Physiol. 2017 Jul 1;595(13):4159-4166. doi:
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38: Dickenson AH, Bannister K. Editorial. Curr Opin Support Palliat Care. 2017
Jun;11(2):105. doi: 10.1097/SPC.0000000000000268. PMID: 28375884.
39: Patel R, Montagut-Bordas C, Dickenson AH. Calcium channel modulation as a
target in chronic pain control. Br J Pharmacol. 2018 Jun;175(12):2173-2184. doi:
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40: Colloca L, Ludman T, Bouhassira D, Baron R, Dickenson AH, Yarnitsky D,
Freeman R, Truini A, Attal N, Finnerup NB, Eccleston C, Kalso E, Bennett DL,
Dworkin RH, Raja SN. Neuropathic pain. Nat Rev Dis Primers. 2017 Feb 16;3:17002.
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41: Bannister K, Lockwood S, Goncalves L, Patel R, Dickenson AH. An
investigation into the inhibitory function of serotonin in diffuse noxious
inhibitory controls in the neuropathic rat. Eur J Pain. 2017 Apr;21(4):750-760.
doi: 10.1002/ejp.979. Epub 2016 Nov 28. PMID: 27891703.
42: Langford RM, Knaggs R, Farquhar-Smith P, Dickenson AH. Is tapentadol
different from classical opioids? A review of the evidence. Br J Pain. 2016
Nov;10(4):217-221. doi: 10.1177/2049463716657363. Epub 2016 Jul 25. PMID:
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43: Sikandar S, Gustavsson Y, Marino MJ, Dickenson AH, Yaksh TL, Sorkin LS,
Ramachandran R. Effects of intraplantar botulinum toxin-B on carrageenan-induced
changes in nociception and spinal phosphorylation of GluA1 and Akt. Eur J
Neurosci. 2016 Jul;44(1):1714-22. doi: 10.1111/ejn.13261. Epub 2016 May 19.
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44: Patel R, Dickenson AH. Neuronal hyperexcitability in the ventral posterior
thalamus of neuropathic rats: modality selective effects of pregabalin. J
Neurophysiol. 2016 Jul 1;116(1):159-70. doi: 10.1152/jn.00237.2016. Epub 2016
Apr 20. PMID: 27098028; PMCID: PMC4961752.
45: Liang M, Lee MC, O'Neill J, Dickenson AH, Iannetti GD. Brain potentials
evoked by intraepidermal electrical stimuli reflect the central sensitization of
nociceptive pathways. J Neurophysiol. 2016 Aug 1;116(2):286-95. doi:
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46: Patel R, Dickenson AH. Mechanisms of the gabapentinoids and α 2 δ-1 calcium
channel subunit in neuropathic pain. Pharmacol Res Perspect. 2016 Feb
27;4(2):e00205. doi: 10.1002/prp2.205. PMID: 27069626; PMCID: PMC4804325.
47: Bannister K, Dickenson AH. What do monoamines do in pain modulation? Curr
Opin Support Palliat Care. 2016 Jun;10(2):143-8. doi:
10.1097/SPC.0000000000000207. PMID: 27043287; PMCID: PMC5604728.
48: Bannister K, Dickenson AH. What the brain tells the spinal cord. Pain. 2016
Oct;157(10):2148-51. doi: 10.1097/j.pain.0000000000000568. PMID: 27023423.
49: Dickenson AH, Baron R. Making sense of sensory profiles. Pain. 2016
Jun;157(6):1177-8. doi: 10.1097/j.pain.0000000000000560. PMID: 26989806.
50: Sikandar S, Aasvang EK, Dickenson AH. Scratching the surface: the processing
of pain from deep tissues. Pain Manag. 2016 Apr;6(2):95-102. doi:
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51: Baron R, Binder A, Attal N, Casale R, Dickenson AH, Treede RD. Neuropathic
low back pain in clinical practice. Eur J Pain. 2016 Jul;20(6):861-73. doi:
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52: Haley JE, Dickenson AH. Evidence for spinal N-methyl-d-aspartate receptor
involvement in prolonged chemical nociception in the rat. Brain Res. 2016 Aug
15;1645:58-60. doi: 10.1016/j.brainres.2016.02.001. Epub 2016 Feb 15. PMID:
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53: Dickenson AH. Special 10th anniversary editorial: pain. Curr Opin Support
Palliat Care. 2016 Mar;10(1):2. doi: 10.1097/SPC.0000000000000193. PMID:
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54: Falk S, Bannister K, Dickenson AH. Cancer pain physiology. Br J Pain. 2014
Nov;8(4):154-62. doi: 10.1177/2049463714545136. PMID: 26516549; PMCID:
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55: Patel R, Brice NL, Lewis RJ, Dickenson AH. Ionic mechanisms of spinal
neuronal cold hypersensitivity in ciguatera. Eur J Neurosci. 2015
Dec;42(11):3004-11. doi: 10.1111/ejn.13098. Epub 2015 Nov 13. PMID: 26454262;
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56: Rahman W, Patel R, Dickenson AH. Electrophysiological evidence for voltage-
gated calcium channel 2 (Cav2) modulation of mechano- and thermosensitive spinal
neuronal responses in a rat model of osteoarthritis. Neuroscience. 2015 Oct
1;305:76-85. doi: 10.1016/j.neuroscience.2015.07.073. Epub 2015 Aug 4. PMID:
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57: DʼMello R, Sand CA, Pezet S, Leiper JM, Gaurilcikaite E, McMahon SB,
Dickenson AH, Nandi M. Dimethylarginine dimethylaminohydrolase 1 is involved in
spinal nociceptive plasticity. Pain. 2015 Oct;156(10):2052-60. doi:
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58: O'Neill J, Sikandar S, McMahon SB, Dickenson AH. Human psychophysics and
rodent spinal neurones exhibit peripheral and central mechanisms of inflammatory
pain in the UVB and UVB heat rekindling models. J Physiol. 2015 Sep
1;593(17):4029-42. doi: 10.1113/JP270294. Epub 2015 Aug 12. PMID: 26047369;
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59: Bannister K, Patel R, Goncalves L, Townson L, Dickenson AH. Diffuse noxious
inhibitory controls and nerve injury: restoring an imbalance between descending
monoamine inhibitions and facilitations. Pain. 2015 Sep;156(9):1803-11. doi:
10.1097/j.pain.0000000000000240. PMID: 26010460.
60: West SJ, Bannister K, Dickenson AH, Bennett DL. Circuitry and plasticity of
the dorsal horn--toward a better understanding of neuropathic pain.
Neuroscience. 2015 Aug 6;300:254-75. doi: 10.1016/j.neuroscience.2015.05.020.
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61: Dickenson AH, Farquhar-Smith PW. Pain: cancer. Curr Opin Support Palliat
Care. 2015 Jun;9(2):97. doi: 10.1097/SPC.0000000000000141. PMID: 25923340.
62: Rahman W, Dickenson AH. Pain: nonmalignant disease. Curr Opin Support
Palliat Care. 2015 Jun;9(2):122-3. doi: 10.1097/SPC.0000000000000138. PMID:
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63: Patel R, Rutten K, Valdor M, Schiene K, Wigge S, Schunk S, Damann N,
Christoph T, Dickenson AH. Electrophysiological characterization of activation
state-dependent Ca(v)2 channel antagonist TROX-1 in spinal nerve injured rats.
Neuroscience. 2015 Jun 25;297:47-57. doi: 10.1016/j.neuroscience.2015.03.057.
Epub 2015 Apr 1. PMID: 25839150; PMCID: PMC4436437.
64: Rahman W, Dickenson AH. Osteoarthritis-dependent changes in antinociceptive
action of Nav1.7 and Nav1.8 sodium channel blockers: An in vivo
electrophysiological study in the rat. Neuroscience. 2015 Jun 4;295:103-16. doi:
10.1016/j.neuroscience.2015.03.042. Epub 2015 Mar 25. PMID: 25818052; PMCID:
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65: Rahman W, Dickenson AH. Emerging targets and therapeutic approaches for the
treatment of osteoarthritis pain. Curr Opin Support Palliat Care. 2015
Jun;9(2):124-30. doi: 10.1097/SPC.0000000000000125. PMID: 25730180.
66: Falk S, Schwab SD, Frøsig-Jørgensen M, Clausen RP, Dickenson AH, Heegaard
AM. P2X7 receptor-mediated analgesia in cancer-induced bone pain. Neuroscience.
2015 Apr 16;291:93-105. doi: 10.1016/j.neuroscience.2015.02.011. Epub 2015 Feb
14. PMID: 25686524.
67: Gonçalves L, Friend LV, Dickenson AH. The influence of μ-opioid and
noradrenaline reuptake inhibition in the modulation of pain responsive neurones
in the central amygdala by tapentadol in rats with neuropathy. Eur J Pharmacol.
2015 Feb 15;749:151-60. doi: 10.1016/j.ejphar.2014.11.032. Epub 2015 Jan 6.
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68: Rahman W, Dickenson AH. Antinociceptive effects of lacosamide on spinal
neuronal and behavioural measures of pain in a rat model of osteoarthritis.
Arthritis Res Ther. 2014 Dec 23;16(6):509. doi: 10.1186/s13075-014-0509-x. PMID:
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69: Little JW, Ford A, Symons-Liguori AM, Chen Z, Janes K, Doyle T, Xie J,
Luongo L, Tosh DK, Maione S, Bannister K, Dickenson AH, Vanderah TW, Porreca F,
Jacobson KA, Salvemini D. Endogenous adenosine A3 receptor activation
selectively alleviates persistent pain states. Brain. 2015 Jan;138(Pt 1):28-35.
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70: Baron R, Dickenson AH. Neuropathic pain: precise sensory profiling improves
treatment and calls for back-translation. Pain. 2014 Nov;155(11):2215-7. doi:
10.1016/j.pain.2014.08.021. Epub 2014 Aug 26. PMID: 25168667.
71: Patel R, Gonçalves L, Leveridge M, Mack SR, Hendrick A, Brice NL, Dickenson
AH. Anti-hyperalgesic effects of a novel TRPM8 agonist in neuropathic rats: a
comparison with topical menthol. Pain. 2014 Oct;155(10):2097-107. doi:
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72: Falk S, Ipsen DH, Appel CK, Ugarak A, Durup D, Dickenson AH, Heegaard AM.
Randall Selitto pressure algometry for assessment of bone-related pain in rats.
Eur J Pain. 2015 Mar;19(3):305-12. doi: 10.1002/ejp.547. PMID: 25057115.
73: Bannister K, Lee YS, Goncalves L, Porreca F, Lai J, Dickenson AH.
Neuropathic plasticity in the opioid and non-opioid actions of dynorphin A
fragments and their interactions with bradykinin B2 receptors on neuronal
activity in the rat spinal cord. Neuropharmacology. 2014 Oct;85:375-83. doi:
10.1016/j.neuropharm.2014.06.005. Epub 2014 Jun 14. PMID: 24937046; PMCID:
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74: Falk S, Patel R, Heegaard A, Mercadante S, Dickenson AH. Spinal neuronal
correlates of tapentadol analgesia in cancer pain: a back-translational
approach. Eur J Pain. 2015 Feb;19(2):152-8. doi: 10.1002/ejp.530. Epub 2014 Jun
11. PMID: 24917026.
75: Falk S, Dickenson AH. Pain and nociception: mechanisms of cancer-induced
bone pain. J Clin Oncol. 2014 Jun 1;32(16):1647-54. doi:
10.1200/JCO.2013.51.7219. Epub 2014 May 5. PMID: 24799469.
76: Gilron I, Dickenson AH. Emerging drugs for neuropathic pain. Expert Opin
Emerg Drugs. 2014 Sep;19(3):329-41. doi: 10.1517/14728214.2014.915025. Epub 2014
May 3. PMID: 24793304.
77: Rahman W, Dickenson AH. Pain: nonmalignant disease. Curr Opin Support
Palliat Care. 2014 Sep;8(3):314-5. doi: 10.1097/SPC.0000000000000052. PMID:
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78: Thakur M, Dickenson AH, Baron R. Osteoarthritis pain: nociceptive or
neuropathic? Nat Rev Rheumatol. 2014 Jun;10(6):374-80. doi:
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79: Patel R, Gonçalves L, Newman R, Jiang FL, Goldby A, Reeve J, Hendrick A,
Teall M, Hannah D, Almond S, Brice N, Dickenson AH. Novel TRPM8 antagonist
attenuates cold hypersensitivity after peripheral nerve injury in rats. J
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2014 Jan 28. PMID: 24472724.
80: Lana B, Schlick B, Martin S, Pratt WS, Page KM, Goncalves L, Rahman W,
Dickenson AH, Bauer CS, Dolphin AC. Differential upregulation in DRG neurons of
an α2δ-1 splice variant with a lower affinity for gabapentin after peripheral
sensory nerve injury. Pain. 2014 Mar;155(3):522-33. doi:
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81: Dickenson AH, Kehlet H. Can we stop pain before it starts? Pain. 2014
Feb;155(2):208-9. doi: 10.1016/j.pain.2013.11.016. Epub 2013 Nov 27. PMID:
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82: Patel R, Bauer CS, Nieto-Rostro M, Margas W, Ferron L, Chaggar K, Crews K,
Ramirez JD, Bennett DL, Schwartz A, Dickenson AH, Dolphin AC. α2δ-1 gene
deletion affects somatosensory neuron function and delays mechanical
hypersensitivity in response to peripheral nerve damage. J Neurosci. 2013 Oct
16;33(42):16412-26. doi: 10.1523/JNEUROSCI.1026-13.2013. PMID: 24133248; PMCID:
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83: Hirsch SJ, Dickenson AH. Morphine sensitivity of spinal neurons in the
chronic constriction injury neuropathic rat pain model. Neurosci Lett. 2014 Mar
6;562:97-101. doi: 10.1016/j.neulet.2013.10.007. Epub 2013 Oct 12. PMID:
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84: Dickenson AH. Commentary on: Opioid and noradrenergic contributions of
tapentadol in experimental neuropathic pain. Neurosci Lett. 2014 Mar 6;562:90.
doi: 10.1016/j.neulet.2013.09.069. Epub 2013 Oct 10. PMID: 24121047.
85: Gilron I, Jensen TS, Dickenson AH. Combination pharmacotherapy for
management of chronic pain: from bench to bedside. Lancet Neurol. 2013
Nov;12(11):1084-95. doi: 10.1016/S1474-4422(13)70193-5. Epub 2013 Sep 25. PMID:
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86: Baron R, Hans G, Dickenson AH. Peripheral input and its importance for
central sensitization. Ann Neurol. 2013 Nov;74(5):630-6. doi: 10.1002/ana.24017.
PMID: 24018757.
87: Tesfaye S, Boulton AJ, Dickenson AH. Mechanisms and management of diabetic
painful distal symmetrical polyneuropathy. Diabetes Care. 2013
Sep;36(9):2456-65. doi: 10.2337/dc12-1964. PMID: 23970715; PMCID: PMC3747929.
88: Rahman W, Dickenson AH. Voltage gated sodium and calcium channel blockers
for the treatment of chronic inflammatory pain. Neurosci Lett. 2013 Dec 17;557
Pt A:19-26. doi: 10.1016/j.neulet.2013.08.004. Epub 2013 Aug 11. PMID: 23941888.
89: Sikandar S, Dickenson AH. II. No need for translation when the same language
is spoken. Br J Anaesth. 2013 Jul;111(1):3-6. doi: 10.1093/bja/aet210. PMID:
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90: Sikandar S, Ronga I, Iannetti GD, Dickenson AH. Neural coding of nociceptive
stimuli-from rat spinal neurones to human perception. Pain. 2013
Aug;154(8):1263-73. doi: 10.1016/j.pain.2013.03.041. Epub 2013 Apr 6. PMID:
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91: Currie GL, Delaney A, Bennett MI, Dickenson AH, Egan KJ, Vesterinen HM, Sena
ES, Macleod MR, Colvin LA, Fallon MT. Animal models of bone cancer pain:
systematic review and meta-analyses. Pain. 2013 Jun;154(6):917-26. doi:
10.1016/j.pain.2013.02.033. Epub 2013 Mar 7. PMID: 23582155.
92: Eijkelkamp N, Linley JE, Torres JM, Bee L, Dickenson AH, Gringhuis M, Minett
MS, Hong GS, Lee E, Oh U, Ishikawa Y, Zwartkuis FJ, Cox JJ, Wood JN. A role for
Piezo2 in EPAC1-dependent mechanical allodynia. Nat Commun. 2013;4:1682. doi:
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93: Sikandar S, Patel R, Patel S, Sikander S, Bennett DL, Dickenson AH. Genes,
molecules and patients--emerging topics to guide clinical pain research. Eur J
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94: Burnham LJ, Dickenson AH. The antinociceptive effect of milnacipran in the
monosodium iodoacetate model of osteoarthritis pain and its relation to changes
in descending inhibition. J Pharmacol Exp Ther. 2013 Mar;344(3):696-707. doi:
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95: O'Neill J, Brock C, Olesen AE, Andresen T, Nilsson M, Dickenson AH.
Unravelling the mystery of capsaicin: a tool to understand and treat pain.
Pharmacol Rev. 2012 Oct;64(4):939-71. doi: 10.1124/pr.112.006163. PMID:
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96: Gonçalves L, Dickenson AH. Asymmetric time-dependent activation of right
central amygdala neurones in rats with peripheral neuropathy and pregabalin
modulation. Eur J Neurosci. 2012 Nov;36(9):3204-13. doi:
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97: Passmore GM, Reilly JM, Thakur M, Keasberry VN, Marsh SJ, Dickenson AH,
Brown DA. Functional significance of M-type potassium channels in nociceptive
cutaneous sensory endings. Front Mol Neurosci. 2012 May 14;5:63. doi:
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98: Sikandar S, Bannister K, Dickenson AH. Brainstem facilitations and
descending serotonergic controls contribute to visceral nociception but not
pregabalin analgesia in rats. Neurosci Lett. 2012 Jun 21;519(1):31-6. doi:
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99: Minett MS, Nassar MA, Clark AK, Passmore G, Dickenson AH, Wang F, Malcangio
M, Wood JN. Distinct Nav1.7-dependent pain sensations require different sets of
sensory and sympathetic neurons. Nat Commun. 2012 Apr 24;3:791. doi:
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100: Thakur M, Rahman W, Hobbs C, Dickenson AH, Bennett DL. Characterisation of
a peripheral neuropathic component of the rat monoiodoacetate model of
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101: Bannister K, Dickenson AH. The double cross of morphine: Stopping OIH in
its tracks. Ann Palliat Med. 2012 Apr;1(1):4-5. doi:
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102: Sikandar S, Dickenson AH. Visceral pain: the ins and outs, the ups and
downs. Curr Opin Support Palliat Care. 2012 Mar;6(1):17-26. doi:
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103: Neziri AY, Dickenmann M, Scaramozzino P, Andersen OK, Arendt-Nielsen L,
Dickenson AH, Curatolo M. Effect of intravenous tropisetron on modulation of
pain and central hypersensitivity in chronic low back pain patients. Pain. 2012
Feb;153(2):311-8. doi: 10.1016/j.pain.2011.10.008. Epub 2011 Nov 17. PMID:
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104: Marchand F, D'Mello R, Yip PK, Calvo M, Muller E, Pezet S, Dickenson AH,
McMahon SB. Specific involvement of atypical PKCζ/PKMζ in spinal persistent
nociceptive processing following peripheral inflammation in rat. Mol Pain. 2011
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105: Dickenson AH, Baron R. Descending controls: insurance against pain? Pain.
2011 Dec;152(12):2677-8. doi: 10.1016/j.pain.2011.07.003. Epub 2011 Aug 15.
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106: Sikandar S, Dickenson AH. Pregabalin modulation of spinal and brainstem
visceral nociceptive processing. Pain. 2011 Oct;152(10):2312-22. doi:
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107: Dickenson AH. Neuropathic Pain. Rev Pain. 2011 Jun;5(2):1-2. doi:
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108: Rahman W, Dickenson AH. Recent Developments in Neuropathic Pain Mechanisms:
Implications for Treatment. Rev Pain. 2011 Jun;5(2):21-5. doi:
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109: Bannister K, Sikandar S, Bauer CS, Dolphin AC, Porreca F, Dickenson AH.
Pregabalin suppresses spinal neuronal hyperexcitability and visceral
hypersensitivity in the absence of peripheral pathophysiology. Anesthesiology.
2011 Jul;115(1):144-52. doi: 10.1097/ALN.0b013e31821f6545. PMID: 21602662;
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110: D'Mello R, Marchand F, Pezet S, McMahon SB, Dickenson AH. Perturbing PSD-95
interactions with NR2B-subtype receptors attenuates spinal nociceptive
plasticity and neuropathic pain. Mol Ther. 2011 Oct;19(10):1780-92. doi:
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111: Rahman W, Bannister K, Bee LA, Dickenson AH. A pronociceptive role for the
5-HT2 receptor on spinal nociceptive transmission: an in vivo
electrophysiological study in the rat. Brain Res. 2011 Mar 25;1382:29-36. doi:
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112: Bee LA, Bannister K, Rahman W, Dickenson AH. Mu-opioid and noradrenergic
α(2)-adrenoceptor contributions to the effects of tapentadol on spinal
electrophysiological measures of nociception in nerve-injured rats. Pain. 2011
Jan;152(1):131-9. doi: 10.1016/j.pain.2010.10.004. Epub 2010 Nov 5. PMID:
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113: Neziri AY, Scaramozzino P, Andersen OK, Dickenson AH, Arendt-Nielsen L,
Curatolo M. Reference values of mechanical and thermal pain tests in a pain-free
population. Eur J Pain. 2011 Apr;15(4):376-83. doi:
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114: Kaan TK, Yip PK, Patel S, Davies M, Marchand F, Cockayne DA, Nunn PA,
Dickenson AH, Ford AP, Zhong Y, Malcangio M, McMahon SB. Systemic blockade of
P2X3 and P2X2/3 receptors attenuates bone cancer pain behaviour in rats. Brain.
2010 Sep;133(9):2549-64. doi: 10.1093/brain/awq194. PMID: 20802203.
115: Asante CO, Dickenson AH. Descending serotonergic facilitation mediated by
spinal 5-HT3 receptors engages spinal rapamycin-sensitive pathways in the rat.
Neurosci Lett. 2010 Oct 29;484(2):108-12. doi: 10.1016/j.neulet.2010.08.024.
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116: Asante CO, Wallace VC, Dickenson AH. Mammalian target of rapamycin
signaling in the spinal cord is required for neuronal plasticity and behavioral
hypersensitivity associated with neuropathy in the rat. J Pain. 2010
Dec;11(12):1356-67. doi: 10.1016/j.jpain.2010.03.013. Epub 2010 May 8. PMID:
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117: Bauer CS, Rahman W, Tran-van-Minh A, Lujan R, Dickenson AH, Dolphin AC. The
anti-allodynic alpha(2)delta ligand pregabalin inhibits the trafficking of the
calcium channel alpha(2)delta-1 subunit to presynaptic terminals in vivo.
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118: Bannister K, Dickenson AH. Opioid hyperalgesia. Curr Opin Support Palliat
Care. 2010 Mar;4(1):1-5. doi: 10.1097/SPC.0b013e328335ddfe. PMID: 20019618.
119: Harvey VL, Caley A, Müller UC, Harvey RJ, Dickenson AH. A Selective Role
for alpha3 Subunit Glycine Receptors in Inflammatory Pain. Front Mol Neurosci.
2009 Nov 4;2:14. doi: 10.3389/neuro.02.014.2009. PMID: 19915732; PMCID:
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120: Bannister K, Bee LA, Dickenson AH. Preclinical and early clinical
investigations related to monoaminergic pain modulation. Neurotherapeutics. 2009
Oct;6(4):703-12. doi: 10.1016/j.nurt.2009.07.009. PMID: 19789074; PMCID:
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121: Rahman W, Bauer CS, Bannister K, Vonsy JL, Dolphin AC, Dickenson AH.
Descending serotonergic facilitation and the antinociceptive effects of
pregabalin in a rat model of osteoarthritic pain. Mol Pain. 2009 Aug 7;5:45.
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122: Bee LA, Dickenson AH. Effects of lacosamide, a novel sodium channel
modulator, on dorsal horn neuronal responses in a rat model of neuropathy.
Neuropharmacology. 2009 Sep;57(4):472-9. doi: 10.1016/j.neuropharm.2009.06.021.
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123: Neziri AY, Andersen OK, Petersen-Felix S, Radanov B, Dickenson AH,
Scaramozzino P, Arendt-Nielsen L, Curatolo M. The nociceptive withdrawal reflex:
normative values of thresholds and reflex receptive fields. Eur J Pain. 2010
Feb;14(2):134-41. doi: 10.1016/j.ejpain.2009.04.010. Epub 2009 Jun 7. PMID:
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124: Asante CO, Wallace VC, Dickenson AH. Formalin-induced behavioural
hypersensitivity and neuronal hyperexcitability are mediated by rapid protein
synthesis at the spinal level. Mol Pain. 2009 Jun 7;5:27. doi:
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125: Harvey VL, Dickenson AH. Behavioural and electrophysiological
characterisation of experimentally induced osteoarthritis and neuropathy in
C57Bl/6 mice. Mol Pain. 2009 Apr 20;5:18. doi: 10.1186/1744-8069-5-18. PMID:
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126: Bauer CS, Nieto-Rostro M, Rahman W, Tran-Van-Minh A, Ferron L, Douglas L,
Kadurin I, Sri Ranjan Y, Fernandez-Alacid L, Millar NS, Dickenson AH, Lujan R,
Dolphin AC. The increased trafficking of the calcium channel subunit
alpha2delta-1 to presynaptic terminals in neuropathic pain is inhibited by the
alpha2delta ligand pregabalin. J Neurosci. 2009 Apr 1;29(13):4076-88. doi:
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127: Nguyen D, Deng P, Matthews EA, Kim DS, Feng G, Dickenson AH, Xu ZC, Luo ZD.
Enhanced pre-synaptic glutamate release in deep-dorsal horn contributes to
calcium channel alpha-2-delta-1 protein-mediated spinal sensitization and
behavioral hypersensitivity. Mol Pain. 2009 Feb 12;5:6. doi:
10.1186/1744-8069-5-6. PMID: 19216737; PMCID: PMC2646710.
128: Bee LA, Dickenson AH. The importance of the descending monoamine system for
the pain experience and its treatment. F1000 Med Rep. 2009 Oct 29;1:83. doi:
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129: Vonsy JL, Ghandehari J, Dickenson AH. Differential analgesic effects of
morphine and gabapentin on behavioural measures of pain and disability in a
model of osteoarthritis pain in rats. Eur J Pain. 2009 Sep;13(8):786-93. doi:
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130: Bee LA, Dickenson AH. Descending facilitation from the brainstem determines
behavioural and neuronal hypersensitivity following nerve injury and efficacy of
pregabalin. Pain. 2008 Nov 15;140(1):209-23. doi: 10.1016/j.pain.2008.08.008.
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131: Harvey VL, Dickenson AH. Mechanisms of pain in nonmalignant disease. Curr
Opin Support Palliat Care. 2008 Jun;2(2):133-9. doi:
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132: Abrahamsen B, Zhao J, Asante CO, Cendan CM, Marsh S, Martinez-Barbera JP,
Nassar MA, Dickenson AH, Wood JN. The cell and molecular basis of mechanical,
cold, and inflammatory pain. Science. 2008 Aug 1;321(5889):702-5. doi:
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133: Gordon-Williams RM, Dickenson AH. Central neuronal mechanisms in cancer-
induced bone pain. Curr Opin Support Palliat Care. 2007 Apr;1(1):6-10. doi:
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134: Ahmedzai SH, Gralla RJ, Dickenson AH. An introduction to Current Opinion in
Supportive and Palliative Care. Curr Opin Support Palliat Care. 2007
Apr;1(1):1-2. doi: 10.1097/SPC.0b013e32814e6c70. PMID: 18660715.
135: Maratou K, Wallace VC, Hasnie FS, Okuse K, Hosseini R, Jina N, Blackbeard
J, Pheby T, Orengo C, Dickenson AH, McMahon SB, Rice AS. Comparison of dorsal
root ganglion gene expression in rat models of traumatic and HIV-associated
neuropathic pain. Eur J Pain. 2009 Apr;13(4):387-98. doi:
10.1016/j.ejpain.2008.05.011. Epub 2008 Jul 7. PMID: 18606552; PMCID:
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136: Urch CE, Dickenson AH. Neuropathic pain in cancer. Eur J Cancer. 2008
May;44(8):1091-6. doi: 10.1016/j.ejca.2008.03.015. PMID: 18492553.
137: Rahman W, Suzuki R, Hunt SP, Dickenson AH. Selective ablation of dorsal
horn NK1 expressing cells reveals a modulation of spinal alpha2-adrenergic
inhibition of dorsal horn neurones. Neuropharmacology. 2008 Jun;54(8):1208-14.
doi: 10.1016/j.neuropharm.2008.03.014. Epub 2008 Apr 8. PMID: 18462764.
138: Pezet S, Marchand F, D'Mello R, Grist J, Clark AK, Malcangio M, Dickenson
AH, Williams RJ, McMahon SB. Phosphatidylinositol 3-kinase is a key mediator of
central sensitization in painful inflammatory conditions. J Neurosci. 2008 Apr
16;28(16):4261-70. doi: 10.1523/JNEUROSCI.5392-07.2008. PMID: 18417706; PMCID:
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139: D'Mello R, Dickenson AH. Spinal cord mechanisms of pain. Br J Anaesth. 2008
Jul;101(1):8-16. doi: 10.1093/bja/aen088. Epub 2008 Apr 15. PMID: 18417503.
140: Perrot S, Dickenson AH, Bennett RM. Fibromyalgia: harmonizing science with
clinical practice considerations. Pain Pract. 2008 May-Jun;8(3):177-89. doi:
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141: Rahman W, D'Mello R, Dickenson AH. Peripheral nerve injury-induced changes
in spinal alpha(2)-adrenoceptor-mediated modulation of mechanically evoked
dorsal horn neuronal responses. J Pain. 2008 Apr;9(4):350-9. doi:
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142: Matthews EA, Bee LA, Stephens GJ, Dickenson AH. The Cav2.3 calcium channel
antagonist SNX-482 reduces dorsal horn neuronal responses in a rat model of
chronic neuropathic pain. Eur J Neurosci. 2007 Jun;25(12):3561-9. doi:
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143: Bee LA, Dickenson AH. Rostral ventromedial medulla control of spinal
sensory processing in normal and pathophysiological states. Neuroscience. 2007
Jul 13;147(3):786-93. doi: 10.1016/j.neuroscience.2007.05.004. Epub 2007 Jun 14.
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144: Altier C, Dale CS, Kisilevsky AE, Chapman K, Castiglioni AJ, Matthews EA,
Evans RM, Dickenson AH, Lipscombe D, Vergnolle N, Zamponi GW. Differential role
of N-type calcium channel splice isoforms in pain. J Neurosci. 2007 Jun
13;27(24):6363-73. doi: 10.1523/JNEUROSCI.0307-07.2007. PMID: 17567797; PMCID:
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145: Rahman W, Sikandar S, Suzuki R, Hunt SP, Dickenson AH. Superficial NK1
expressing spinal dorsal horn neurones modulate inhibitory neurotransmission
mediated by spinal GABA(A) receptors. Neurosci Lett. 2007 Jun 4;419(3):278-83.
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146: Rojas-Piloni G, Dickenson AH, Condés-Lara M. Superficial dorsal horn
neurons with double spike activity in the rat. Neurosci Lett. 2007 May
29;419(2):147-52. doi: 10.1016/j.neulet.2007.04.032. Epub 2007 Apr 18. PMID:
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147: Hasnie FS, Breuer J, Parker S, Wallace V, Blackbeard J, Lever I,
Kinchington PR, Dickenson AH, Pheby T, Rice AS. Further characterization of a
rat model of varicella zoster virus-associated pain: Relationship between
mechanical hypersensitivity and anxiety-related behavior, and the influence of
analgesic drugs. Neuroscience. 2007 Feb 23;144(4):1495-508. doi:
10.1016/j.neuroscience.2006.11.029. Epub 2006 Dec 29. PMID: 17197105; PMCID:
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148: Dickenson AH, Ghandehari J. Anti-convulsants and anti-depressants. Handb
Exp Pharmacol. 2007;(177):145-77. doi: 10.1007/978-3-540-33823-9_6. PMID:
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149: Foulkes T, Nassar MA, Lane T, Matthews EA, Baker MD, Gerke V, Okuse K,
Dickenson AH, Wood JN. Deletion of annexin 2 light chain p11 in nociceptors
causes deficits in somatosensory coding and pain behavior. J Neurosci. 2006 Oct
11;26(41):10499-507. doi: 10.1523/JNEUROSCI.1997-06.2006. PMID: 17035534; PMCID:
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150: Suzuki R, Porreca F, Dickenson AH. Evidence for spinal dorsal horn
hyperexcitability in rats following sustained morphine exposure. Neurosci Lett.
2006 Oct 23;407(2):156-61. doi: 10.1016/j.neulet.2006.08.027. Epub 2006 Sep 7.
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151: Rygh LJ, Suzuki R, Rahman W, Wong Y, Vonsy JL, Sandhu H, Webber M, Hunt S,
Dickenson AH. Local and descending circuits regulate long-term potentiation and
zif268 expression in spinal neurons. Eur J Neurosci. 2006 Aug;24(3):761-72. doi:
10.1111/j.1460-9568.2006.04968.x. PMID: 16930406.
152: Li CY, Zhang XL, Matthews EA, Li KW, Kurwa A, Boroujerdi A, Gross J, Gold
MS, Dickenson AH, Feng G, Luo ZD. Calcium channel alpha2delta1 subunit mediates
spinal hyperexcitability in pain modulation. Pain. 2006 Nov;125(1-2):20-34. doi:
10.1016/j.pain.2006.04.022. Epub 2006 Jun 9. PMID: 16764990; PMCID: PMC1635965.
153: Rahman W, Suzuki R, Webber M, Hunt SP, Dickenson AH. Depletion of
endogenous spinal 5-HT attenuates the behavioural hypersensitivity to mechanical
and cooling stimuli induced by spinal nerve ligation. Pain. 2006
Aug;123(3):264-74. doi: 10.1016/j.pain.2006.02.033. Epub 2006 Apr 27. PMID:
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154: Matthews EA, Wood JN, Dickenson AH. Na(v) 1.8-null mice show stimulus-
dependent deficits in spinal neuronal activity. Mol Pain. 2006 Feb 14;2:5. doi:
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155: Suzuki R, Dickenson AH. Differential pharmacological modulation of the
spontaneous stimulus-independent activity in the rat spinal cord following
peripheral nerve injury. Exp Neurol. 2006 Mar;198(1):72-80. doi:
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156: Dickenson AH, Bee LA, Suzuki R. Pains, gains, and midbrains. Proc Natl Acad
Sci U S A. 2005 Dec 13;102(50):17885-6. doi: 10.1073/pnas.0508494102. Epub 2005
Dec 5. PMID: 16330782; PMCID: PMC1312401.
157: Urch CE, Donovan-Rodriguez T, Gordon-Williams R, Bee LA, Dickenson AH.
Efficacy of chronic morphine in a rat model of cancer-induced bone pain:
behavior and in dorsal horn pathophysiology. J Pain. 2005 Dec;6(12):837-45. doi:
10.1016/j.jpain.2005.08.005. PMID: 16326372.
158: Donovan-Rodriguez T, Urch CE, Dickenson AH. Evidence of a role for
descending serotonergic facilitation in a rat model of cancer-induced bone pain.
Neurosci Lett. 2006 Jan 30;393(2-3):237-42. doi: 10.1016/j.neulet.2005.09.073.
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159: Suzuki R, Rahman W, Rygh LJ, Webber M, Hunt SP, Dickenson AH. Spinal-
supraspinal serotonergic circuits regulating neuropathic pain and its treatment
with gabapentin. Pain. 2005 Oct;117(3):292-303. doi: 10.1016/j.pain.2005.06.015.
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160: Dickenson AH, Carpenter K, Suzuki R. Pain relief. IDrugs. 1999
Nov;2(11):1130-2. PMID: 16113982.
161: Condés-Lara M, Maie IA, Dickenson AH. Oxytocin actions on afferent evoked
spinal cord neuronal activities in neuropathic but not in normal rats. Brain
Res. 2005 May 31;1045(1-2):124-33. doi: 10.1016/j.brainres.2005.03.020. Epub
2005 Apr 21. PMID: 15910770.
162: Bahia PK, Suzuki R, Benton DC, Jowett AJ, Chen MX, Trezise DJ, Dickenson
AH, Moss GW. A functional role for small-conductance calcium-activated potassium
channels in sensory pathways including nociceptive processes. J Neurosci. 2005
Apr 6;25(14):3489-98. doi: 10.1523/JNEUROSCI.0597-05.2005. PMID: 15814779;
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163: Dickenson AH, Suzuki R. Opioids in neuropathic pain: clues from animal
studies. Eur J Pain. 2005 Apr;9(2):113-6. doi: 10.1016/j.ejpain.2004.05.004.
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164: Hansson PT, Dickenson AH. Pharmacological treatment of peripheral
neuropathic pain conditions based on shared commonalities despite multiple
etiologies. Pain. 2005 Feb;113(3):251-4. doi: 10.1016/j.pain.2004.10.007. PMID:
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165: Stirling LC, Forlani G, Baker MD, Wood JN, Matthews EA, Dickenson AH,
Nassar MA. Nociceptor-specific gene deletion using heterozygous NaV1.8-Cre
recombinase mice. Pain. 2005 Jan;113(1-2):27-36. doi:
10.1016/j.pain.2004.08.015. PMID: 15621361.
166: Donovan-Rodriguez T, Dickenson AH, Urch CE. Gabapentin normalizes spinal
neuronal responses that correlate with behavior in a rat model of cancer-induced
bone pain. Anesthesiology. 2005 Jan;102(1):132-40. doi:
10.1097/00000542-200501000-00022. PMID: 15618797.
167: Suzuki R, Rygh LJ, Dickenson AH. Bad news from the brain: descending 5-HT
pathways that control spinal pain processing. Trends Pharmacol Sci. 2004
Dec;25(12):613-7. doi: 10.1016/j.tips.2004.10.002. PMID: 15530638.
168: Nassar MA, Stirling LC, Forlani G, Baker MD, Matthews EA, Dickenson AH,
Wood JN. Nociceptor-specific gene deletion reveals a major role for Nav1.7 (PN1)
in acute and inflammatory pain. Proc Natl Acad Sci U S A. 2004 Aug
24;101(34):12706-11. doi: 10.1073/pnas.0404915101. Epub 2004 Aug 16. PMID:
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169: Suzuki R, Rahman W, Hunt SP, Dickenson AH. Descending facilitatory control
of mechanically evoked responses is enhanced in deep dorsal horn neurones
following peripheral nerve injury. Brain Res. 2004 Sep 3;1019(1-2):68-76. doi:
10.1016/j.brainres.2004.05.108. PMID: 15306240.
170: Rahman W, Suzuki R, Rygh LJ, Dickenson AH. Descending serotonergic
facilitation mediated through rat spinal 5HT3 receptors is unaltered following
carrageenan inflammation. Neurosci Lett. 2004 May 6;361(1-3):229-31. doi:
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171: Stanfa LC, Dickenson AH. In vivo electrophysiology of dorsal-horn neurons.
Methods Mol Med. 2004;99:139-53. doi: 10.1007/978-1-59259-770-3_12. PMID:
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172: Seagrove LC, Suzuki R, Dickenson AH. Electrophysiological characterisations
of rat lamina I dorsal horn neurones and the involvement of excitatory amino
acid receptors. Pain. 2004 Mar;108(1-2):76-87. doi: 10.1016/j.pain.2003.12.004.
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173: Donovan-Rodriguez T, Dickenson AH, Urch CE. Superficial dorsal horn
neuronal responses and the emergence of behavioural hyperalgesia in a rat model
of cancer-induced bone pain. Neurosci Lett. 2004 Apr 22;360(1-2):29-32. doi:
10.1016/j.neulet.2004.01.048. PMID: 15082171.
174: Matthews EA, Dickenson AH. Effects of spinally administered adenine on
dorsal horn neuronal responses in a rat model of inflammation. Neurosci Lett.
2004 Feb 19;356(3):211-4. doi: 10.1016/j.neulet.2003.11.057. PMID: 15036632.
175: Suzuki R, Edwards M, Dickenson AH. ReN-1869 [(R)-1-(3-(10,11-dihydro-5H-dib
enzo[a,d]cyclohepten-5-ylidene)-1-propyl)-3-piperidine carboxylic acid], a novel
histamine H1 receptor antagonist, produces potent and selective antinociceptive
effects on dorsal horn neurons after inflammation and neuropathy. J Pharmacol
Exp Ther. 2004 Jun;309(3):1230-8. doi: 10.1124/jpet.103.063511. Epub 2004 Feb
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176: Maie IA, Dickenson AH. Cholecystokinin fails to block the spinal inhibitory
effects of nociceptin in sham operated and neuropathic rats. Eur J Pharmacol.
2004 Jan 26;484(2-3):235-40. doi: 10.1016/j.ejphar.2003.11.030. PMID: 14744608.
177: Flatters SJ, Fox AJ, Dickenson AH. Nerve injury alters the effects of
interleukin-6 on nociceptive transmission in peripheral afferents. Eur J
Pharmacol. 2004 Jan 26;484(2-3):183-91. doi: 10.1016/j.ejphar.2003.11.013. PMID:
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178: Urch CE, Donovan-Rodriguez T, Dickenson AH. Alterations in dorsal horn
neurones in a rat model of cancer-induced bone pain. Pain. 2003
Dec;106(3):347-56. doi: 10.1016/j.pain.2003.08.002. PMID: 14659517.
179: Suzuki R, Green GM, Millan MJ, Dickenson AH. Electrophysiologic
characterization of the antinociceptive actions of S18616, a novel and potent
alpha 2-adrenoceptor agonist, after acute and persistent pain states. J Pain.
2002 Jun;3(3):234-43. doi: 10.1054/jpai.2002.123651. PMID: 14622778.
180: Suzuki R, Hunt SP, Dickenson AH. The coding of noxious mechanical and
thermal stimuli of deep dorsal horn neurones is attenuated in NK1 knockout mice.
Neuropharmacology. 2003 Dec;45(8):1093-100. doi: 10.1016/s0028-3908(03)00281-8.
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181: Urch CE, Dickenson AH. Neuronal nitric oxide synthase modulation of dorsal
horn neuronal responses in the rat: a developmental study. Dev Neurosci. 2003
Sep-Oct;25(5):301-7. doi: 10.1159/000073506. PMID: 14614256.
182: Carpenter KJ, Sen S, Matthews EA, Flatters SL, Wozniak KM, Slusher BS,
Dickenson AH. Effects of GCP-II inhibition on responses of dorsal horn neurones
after inflammation and neuropathy: an electrophysiological study in the rat.
Neuropeptides. 2003 Oct;37(5):298-306. doi: 10.1016/j.npep.2003.08.001. PMID:
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183: McCleane GJ, Suzuki R, Dickenson AH. Does a single intravenous injection of
the 5HT3 receptor antagonist ondansetron have an analgesic effect in neuropathic
pain? A double-blinded, placebo-controlled cross-over study. Anesth Analg. 2003
Nov;97(5):1474-8. doi: 10.1213/01.ane.0000085640.69855.51. PMID: 14570668.
184: Flatters SJ, Fox AJ, Dickenson AH. Spinal interleukin-6 (IL-6) inhibits
nociceptive transmission following neuropathy. Brain Res. 2003 Sep
12;984(1-2):54-62. doi: 10.1016/s0006-8993(03)03092-0. PMID: 12932839.
185: Urch CE, Dickenson AH. In vivo single unit extracellular recordings from
spinal cord neurones of rats. Brain Res Brain Res Protoc. 2003 Aug;12(1):26-34.
doi: 10.1016/s1385-299x(03)00068-0. PMID: 12928042.
186: Passmore GM, Selyanko AA, Mistry M, Al-Qatari M, Marsh SJ, Matthews EA,
Dickenson AH, Brown TA, Burbidge SA, Main M, Brown DA. KCNQ/M currents in
sensory neurons: significance for pain therapy. J Neurosci. 2003 Aug
6;23(18):7227-36. doi: 10.1523/JNEUROSCI.23-18-07227.2003. PMID: 12904483;
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187: Flatters SJ, Fox AJ, Dickenson AH. In vivo and in vitro effects of
peripheral galanin on nociceptive transmission in naive and neuropathic states.
Neuroscience. 2003;116(4):1005-12. doi: 10.1016/s0306-4522(02)00947-8. PMID:
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188: Suzuki R, Morcuende S, Webber M, Hunt SP, Dickenson AH. Superficial
NK1-expressing neurons control spinal excitability through activation of
descending pathways. Nat Neurosci. 2002 Dec;5(12):1319-26. doi: 10.1038/nn966.
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189: Dickenson AH. Gate control theory of pain stands the test of time. Br J
Anaesth. 2002 Jun;88(6):755-7. doi: 10.1093/bja/88.6.755. PMID: 12173188.
190: Flatters SJ, Fox AJ, Dickenson AH. Nerve injury induces plasticity that
results in spinal inhibitory effects of galanin. Pain. 2002 Aug;98(3):249-58.
doi: 10.1016/s0304-3959(02)00180-x. Erratum in: Pain 2002 Oct;99(3):611-3. PMID:
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191: Suzuki R, Dickenson AH. Neuropharmacologic targets and agents in
fibromyalgia. Curr Pain Headache Rep. 2002 Aug;6(4):267-73. doi:
10.1007/s11916-002-0047-0. PMID: 12095461.
192: Carpenter KJ, Dickenson AH. Molecular aspects of pain research.
Pharmacogenomics J. 2002;2(2):87-95. doi: 10.1038/sj.tpj.6500095. PMID:
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193: Suzuki R, Dickenson AH. Nerve injury-induced changes in opioid modulation
of wide dynamic range dorsal column nuclei neurones. Neuroscience.
2002;111(1):215-28. doi: 10.1016/s0306-4522(01)00617-0. PMID: 11955724.
194: Dickenson AH, Matthews EA, Suzuki R. Neurobiology of neuropathic pain: mode
of action of anticonvulsants. Eur J Pain. 2002;6 Suppl A:51-60. doi:
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195: Matthews EA, Dickenson AH. A combination of gabapentin and morphine
mediates enhanced inhibitory effects on dorsal horn neuronal responses in a rat
model of neuropathy. Anesthesiology. 2002 Mar;96(3):633-40. doi:
10.1097/00000542-200203000-00020. PMID: 11873039.
196: Carpenter KJ, Dickenson AH. Amino acids are still as exciting as ever. Curr
Opin Pharmacol. 2001 Feb;1(1):57-61. doi: 10.1016/s1471-4892(01)00009-1. PMID:
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197: Matthews EA, Dickenson AH. Effects of spinally delivered N- and P-type
voltage-dependent calcium channel antagonists on dorsal horn neuronal responses
in a rat model of neuropathy. Pain. 2001 May;92(1-2):235-46. doi:
10.1016/s0304-3959(01)00255-x. PMID: 11323145.
198: Matthews EA, Dickenson AH. Effects of ethosuximide, a T-type Ca(2+) channel
blocker, on dorsal horn neuronal responses in rats. Eur J Pharmacol. 2001
Mar;415(2-3):141-9. doi: 10.1016/s0014-2999(01)00812-3. PMID: 11274992.
199: Suzuki R, Stanfa LC, Kowaluk EA, Williams M, Jarvis MF, Dickenson AH. The
effect of ABT-702, a novel adenosine kinase inhibitor, on the responses of
spinal neurones following carrageenan inflammation and peripheral nerve injury.
Br J Pharmacol. 2001 Apr;132(7):1615-23. doi: 10.1038/sj.bjp.0703972. PMID:
11264257; PMCID: PMC1572706.
200: Suzuki R, Matthews EA, Dickenson AH. Comparison of the effects of MK-801,
ketamine and memantine on responses of spinal dorsal horn neurones in a rat
model of mononeuropathy. Pain. 2001 Mar;91(1-2):101-9. doi:
10.1016/s0304-3959(00)00423-1. PMID: 11240082.
201: Kontinen VK, Stanfa LC, Basu A, Dickenson AH. Electrophysiologic evidence
for increased endogenous gabaergic but not glycinergic inhibitory tone in the
rat spinal nerve ligation model of neuropathy. Anesthesiology. 2001
Feb;94(2):333-9. doi: 10.1097/00000542-200102000-00024. PMID: 11176099.
202: Urch CE, Rahman W, Dickenson AH. Electrophysiological studies on the role
of the NMDA receptor in nociception in the developing rat spinal cord. Brain Res
Dev Brain Res. 2001 Jan 31;126(1):81-9. doi: 10.1016/s0165-3806(00)00141-3.
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203: Carpenter KJ, Nandi M, Dickenson AH. Peripheral administration of low pH
solutions causes activation and sensitisation of convergent dorsal horn neurones
in the anaesthetised rat. Neurosci Lett. 2001 Feb 9;298(3):179-82. doi:
10.1016/s0304-3940(00)01759-6. PMID: 11165436.
204: Stanfa LC, Hampton DW, Dickenson AH. Role of Ca2+-permeable non-NMDA
glutamate receptors in spinal nociceptive transmission. Neuroreport. 2000 Sep
28;11(14):3199-202. doi: 10.1097/00001756-200009280-00030. PMID: 11043548.
205: Suzuki R, Dickenson AH. Neuropathic pain: nerves bursting with excitement
.. Neuroreport. 2000 Aug 21;11(12):R17-21. doi:
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206: Rygh LJ, Kontinen VK, Suzuki R, Dickenson AH. Different increase in C-fibre
evoked responses after nociceptive conditioning stimulation in sham-operated and
neuropathic rats. Neurosci Lett. 2000 Jul 14;288(2):99-102. doi:
10.1016/s0304-3940(00)01201-5. PMID: 10876070.
207: Dickenson AH, Stanfa LC, Kontinen V, Suzuki R, Carpenter K. Comment on:
Svendsen et al; some problems with wind-up and its calculation, PAIN 83 (1999)
109-111. Pain. 2000 Apr;85(3):524. doi: 10.1016/s0304-3959(99)00291-2. PMID:
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208: Carpenter KJ, Chapman V, Dickenson AH. Neuronal inhibitory effects of
methadone are predominantly opioid receptor mediated in the rat spinal cord in
vivo. Eur J Pain. 2000;4(1):19-26. doi: 10.1053/eujp.1999.0147. PMID: 10833552.
209: Suzuki R, Kontinen VK, Matthews E, Williams E, Dickenson AH. Enlargement of
the receptive field size to low intensity mechanical stimulation in the rat
spinal nerve ligation model of neuropathy. Exp Neurol. 2000 Jun;163(2):408-13.
doi: 10.1006/exnr.2000.7371. PMID: 10833315.
210: Carpenter KJ, Vithlani M, Dickenson AH. Unaltered peripheral excitatory
actions of nociceptin contrast with enhanced spinal inhibitory effects after
carrageenan inflammation: an electrophysiological study in the rat. Pain. 2000
Apr;85(3):433-41. doi: 10.1016/s0304-3959(99)00301-2. PMID: 10781916.
211: Kontinen VK, Dickenson AH. Effects of midazolam in the spinal nerve
ligation model of neuropathic pain in rats. Pain. 2000 Apr;85(3):425-31. doi:
10.1016/s0304-3959(99)00298-5. PMID: 10781915.
212: Stanfa LC, Kontinen VK, Dickenson AH. Effects of spinally administered P2X
receptor agonists and antagonists on the responses of dorsal horn neurones
recorded in normal, carrageenan-inflamed and neuropathic rats. Br J Pharmacol.
2000 Jan;129(2):351-9. doi: 10.1038/sj.bjp.0703047. PMID: 10694242; PMCID:
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213: Rygh LJ, Green M, Athauda N, Tjølsen A, Dickenson AH. Effect of spinal
morphine after long-term potentiation of wide dynamic range neurones in the rat.
Anesthesiology. 2000 Jan;92(1):140-6. doi: 10.1097/00000542-200001000-00025.
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214: Carpenter KJ, Dickenson AH. NMDA receptors and pain--hopes for novel
analgesics. Reg Anesth Pain Med. 1999 Nov-Dec;24(6):506-8. doi:
10.1016/s1098-7339(99)90039-1. PMID: 10588552.
215: Stanfa LC, Dickenson AH. The role of non-N-methyl-D-aspartate ionotropic
glutamate receptors in the spinal transmission of nociception in normal animals
and animals with carrageenan inflammation. Neuroscience. 1999;93(4):1391-8. doi:
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216: Rahman W, Dickenson AH. Development of spinal opioid systems. Reg Anesth
Pain Med. 1999 Sep-Oct;24(5):383-5. doi: 10.1016/s1098-7339(99)90001-9. PMID:
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217: Chizh BA, Dickenson AH, Wnendt S. The race to control pain: more
participants, more targets. Trends Pharmacol Sci. 1999 Sep;20(9):354-7. doi:
10.1016/s0165-6147(99)01378-4. PMID: 10462755.
218: Akopian AN, Souslova V, England S, Okuse K, Ogata N, Ure J, Smith A, Kerr
BJ, McMahon SB, Boyce S, Hill R, Stanfa LC, Dickenson AH, Wood JN. The
tetrodotoxin-resistant sodium channel SNS has a specialized function in pain
pathways. Nat Neurosci. 1999 Jun;2(6):541-8. doi: 10.1038/9195. PMID: 10448219.
219: Rahman W, Dickenson AH. Electrophysiological studies on the postnatal
development of the spinal antinociceptive effects of the delta opioid receptor
agonist DPDPE in the rat. Br J Pharmacol. 1999 Mar;126(5):1115-22. doi:
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220: Suzuki R, Chapman V, Dickenson AH. The effectiveness of spinal and systemic
morphine on rat dorsal horn neuronal responses in the spinal nerve ligation
model of neuropathic pain. Pain. 1999 Mar;80(1-2):215-28. doi:
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221: Dickenson AH. Plasticity: implications for opioid and other pharmacological
interventions in specific pain states. Behav Brain Sci. 1997 Sep;20(3):392-403;
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222: Carpenter KJ, Dickenson AH. Evidence that [Phe1
psi(CH2-NH)Gly2]nociceptin-(1-13)-NH2, a peripheral ORL-1 receptor antagonist,
acts as an agonist in the rat spinal cord. Br J Pharmacol. 1998
Nov;125(5):949-51. doi: 10.1038/sj.bjp.0702188. PMID: 9846631; PMCID:
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223: Chapman V, Ng J, Dickenson AH. A novel spinal action of mexiletine in
spinal somatosensory transmission of nerve injured rats. Pain. 1998
Sep;77(3):289-96. doi: 10.1016/s0304-3959(98)00106-7. PMID: 9808354.
224: Rahman W, Dashwood MR, Fitzgerald M, Aynsley-Green A, Dickenson AH.
Postnatal development of multiple opioid receptors in the spinal cord and
development of spinal morphine analgesia. Brain Res Dev Brain Res. 1998 Jun
15;108(1-2):239-54. doi: 10.1016/s0165-3806(98)00054-6. PMID: 9693800.
225: Ebert B, Andersen S, Hjeds H, Dickenson AH. Dextropropoxyphene acts as a
noncompetitive N-methyl-D-aspartate antagonist. J Pain Symptom Manage. 1998
May;15(5):269-74. doi: 10.1016/s0885-3924(98)00015-3. PMID: 9654831.
226: Green GM, Lyons L, Dickenson AH. Alpha2-adrenoceptor antagonists enhance
responses of dorsal horn neurones to formalin induced inflammation. Eur J
Pharmacol. 1998 Apr 24;347(2-3):201-4. doi: 10.1016/s0014-2999(98)00217-9. PMID:
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227: Stanfa LC, Dickenson AH. Inflammation alters the effects of mGlu receptor
agonists on spinal nociceptive neurones. Eur J Pharmacol. 1998 Apr
24;347(2-3):165-72. doi: 10.1016/s0014-2999(98)00098-3. PMID: 9653877.
228: Chapman V, Suzuki R, Dickenson AH. Electrophysiological characterization of
spinal neuronal response properties in anaesthetized rats after ligation of
spinal nerves L5-L6. J Physiol. 1998 Mar 15;507 ( Pt 3)(Pt 3):881-94. doi:
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229: Chapman V, Suzuki R, Chamarette HL, Rygh LJ, Dickenson AH. Effects of
systemic carbamazepine and gabapentin on spinal neuronal responses in spinal
nerve ligated rats. Pain. 1998 Apr;75(2-3):261-72. doi:
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230: Reeve AJ, Dickenson AH, Kerr NC. Spinal effects of bicuculline: modulation
of an allodynia-like state by an A1-receptor agonist, morphine, and an NMDA-
receptor antagonist. J Neurophysiol. 1998 Mar;79(3):1494-507. doi:
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231: Bannon AW, Decker MW, Holladay MW, Curzon P, Donnelly-Roberts D,
Puttfarcken PS, Bitner RS, Diaz A, Dickenson AH, Porsolt RD, Williams M, Arneric
SP. Broad-spectrum, non-opioid analgesic activity by selective modulation of
neuronal nicotinic acetylcholine receptors. Science. 1998 Jan 2;279(5347):77-81.
doi: 10.1126/science.279.5347.77. PMID: 9417028.
232: Chapman V, Diaz A, Dickenson AH. Distinct inhibitory effects of spinal
endomorphin-1 and endomorphin-2 on evoked dorsal horn neuronal responses in the
rat. Br J Pharmacol. 1997 Dec;122(8):1537-9. doi: 10.1038/sj.bjp.0701594. PMID:
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233: Diaz A, Mayet S, Dickenson AH. BU-224 produces spinal antinociception as an
agonist at imidazoline I2 receptors. Eur J Pharmacol. 1997 Aug 20;333(1):9-15.
doi: 10.1016/s0014-2999(97)01118-7. PMID: 9311655.
234: Chapman V, Wildman MA, Dickenson AH. Distinct electrophysiological effects
of two spinally administered membrane stabilising drugs, bupivacaine and
lamotrigine. Pain. 1997 Jul;71(3):285-95. doi: 10.1016/s0304-3959(97)03365-4.
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235: Dickenson AH, Chapman V, Green GM. The pharmacology of excitatory and
inhibitory amino acid-mediated events in the transmission and modulation of pain
in the spinal cord. Gen Pharmacol. 1997 May;28(5):633-8. doi:
10.1016/s0306-3623(96)00359-x. PMID: 9184794.
236: Chapman V, Dickenson AH. Inflammation reveals inhibition of noxious
responses of rat spinal neurones by carbamazepine. Neuroreport. 1997 Apr
14;8(6):1399-404. doi: 10.1097/00001756-199704140-00016. PMID: 9172143.
237: Stanfa LC, Singh L, Williams RG, Dickenson AH. Gabapentin, ineffective in
normal rats, markedly reduces C-fibre evoked responses after inflammation.
Neuroreport. 1997 Feb 10;8(3):587-90. doi: 10.1097/00001756-199702100-00002.
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238: Dickenson AH. NMDA receptor antagonists: interactions with opioids. Acta
Anaesthesiol Scand. 1997 Jan;41(1 Pt 2):112-5. doi:
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239: Diaz A, Dickenson AH. Blockade of spinal N- and P-type, but not L-type,
calcium channels inhibits the excitability of rat dorsal horn neurones produced
by subcutaneous formalin inflammation. Pain. 1997 Jan;69(1-2):93-100. doi:
10.1016/s0304-3959(96)03271-x. PMID: 9060018.
240: Stanfa LC, Misra C, Dickenson AH. Amplification of spinal nociceptive
transmission depends on the generation of nitric oxide in normal and carrageenan
rats. Brain Res. 1996 Oct 21;737(1-2):92-8. doi: 10.1016/0006-8993(96)00629-4.
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241: Andersen S, Dickenson AH, Kohn M, Reeve A, Rahman W, Ebert B. The opioid
ketobemidone has a NMDA blocking effect. Pain. 1996 Oct;67(2-3):369-74. doi:
10.1016/0304-3959(96)03123-5. PMID: 8951931.
242: Boxall SJ, Thompson SW, Dray A, Dickenson AH, Urban L. Metabotropic
glutamate receptor activation contributes to nociceptive reflex activity in the
rat spinal cord in vitro. Neuroscience. 1996 Sep;74(1):13-20. doi:
10.1016/0306-4522(96)00101-7. PMID: 8843073.
243: Stanfa LC, Chapman V, Kerr N, Dickenson AH. Inhibitory action of nociceptin
on spinal dorsal horn neurones of the rat, in vivo. Br J Pharmacol. 1996
Aug;118(8):1875-7. doi: 10.1111/j.1476-5381.1996.tb15618.x. PMID: 8864517;
PMCID: PMC1909884.
244: Dickenson AH. Balances between excitatory and inhibitory events in the
spinal cord and chronic pain. Prog Brain Res. 1996;110:225-31. doi:
10.1016/s0079-6123(08)62577-7. PMID: 9000728.
245: Dickenson AH. Opioid receptors: electrophysiological and neurophysiological
approaches. Acta Anaesthesiol Belg. 1996;47(3):101-4. PMID: 8959193.
246: Chapman V, Dickenson AH. Time-related roles of excitatory amino acid
receptors during persistent noxiously evoked responses of rat dorsal horn
neurones. Brain Res. 1995 Dec 12;703(1-2):45-50. doi:
10.1016/0006-8993(95)01063-7. PMID: 8719614.
247: Reeve AJ, Dickenson AH. The roles of spinal adenosine receptors in the
control of acute and more persistent nociceptive responses of dorsal horn
neurones in the anaesthetized rat. Br J Pharmacol. 1995 Oct;116(4):2221-8. doi:
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248: Dickenson AH. Spinal cord pharmacology of pain. Br J Anaesth. 1995
Aug;75(2):193-200. doi: 10.1093/bja/75.2.193. PMID: 7577253.
249: Reeve AJ, Dickenson AH. Electrophysiological study on spinal
antinociceptive interactions between adenosine and morphine in the dorsal horn
of the rat. Neurosci Lett. 1995 Jul 14;194(1-2):81-4. doi:
10.1016/0304-3940(95)11732-c. PMID: 7478219.
250: Dickenson AH. Central acute pain mechanisms. Ann Med. 1995 Apr;27(2):223-7.
doi: 10.3109/07853899509031963. PMID: 7632418.
251: Chapman V, Haley JE, Dickenson AH. Electrophysiologic analysis of
preemptive effects of spinal opioids on N-methyl-D-aspartate receptor-mediated
events. Anesthesiology. 1994 Dec;81(6):1429-35. doi:
10.1097/00000542-199412000-00018. PMID: 7992912.
252: Dickenson AH. O lokalizatsii i mekhanizmakh deĭstviia opioidov [The
localization and mechanisms of action of opioids]. Eksp Klin Farmakol. 1994 Nov-
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253: Sullivan AF, Hewett K, Dickenson AH. Differential modulation of alpha
2-adrenergic and opioid spinal antinociception by cholecystokinin and
cholecystokinin antagonists in the rat dorsal horn: an electrophysiological
study. Brain Res. 1994 Oct 31;662(1-2):141-7. doi: 10.1016/0006-8993(94)90806-0.
PMID: 7859067.
254: Chapman V, Dickenson AH, Tjølsen A. Bi-directional effects of intrathecal
NMDA and substance P on rat dorsal horn neuronal responses. Neurosci Lett. 1994
Aug 29;178(1):90-4. doi: 10.1016/0304-3940(94)90297-6. PMID: 7529389.
255: Chapman V, Dickenson AH. Enhanced responses of rat dorsal horn neurons
after UV irradiation of the hindpaw; roles of the NMDA receptor. Neurosci Lett.
1994 Jul 18;176(1):41-4. doi: 10.1016/0304-3940(94)90866-4. PMID: 7970233.
256: Devillers JP, Mazarguil H, Allard M, Dickenson AH, Zajac JM, Simonnet G.
Characterization of a potent agonist for NPFF receptors: binding study on rat
spinal cord membranes. Neuropharmacology. 1994 May;33(5):661-9. doi:
10.1016/0028-3908(94)90172-4. PMID: 7936102.
257: Stanfa LC, Dickenson AH. Electrophysiological studies on the spinal roles
of endogenous opioids in carrageenan inflammation. Pain. 1994 Feb;56(2):185-91.
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258: Stanfa LC, Dickenson AH. Enhanced alpha-2 adrenergic controls and spinal
morphine potency in inflammation. Neuroreport. 1994 Jan 12;5(4):469-72. doi:
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259: Dickenson AH. Neurophysiology of opioid poorly responsive pain. Cancer
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260: Chapman V, Dickenson AH. The effect of intrathecal administration of
RP67580, a potent neurokinin 1 antagonist on nociceptive transmission in the rat
spinal cord. Neurosci Lett. 1993 Jul 23;157(2):149-52. doi:
10.1016/0304-3940(93)90724-y. PMID: 8233046.
261: Kalso EA, Sullivan AF, McQuay HJ, Dickenson AH, Roques BP. Cross-tolerance
between mu opioid and alpha-2 adrenergic receptors, but not between mu and delta
opioid receptors in the spinal cord of the rat. J Pharmacol Exp Ther. 1993
May;265(2):551-8. PMID: 8098759.
262: Stanfa LC, Dickenson AH. Cholecystokinin as a factor in the enhanced
potency of spinal morphine following carrageenin inflammation. Br J Pharmacol.
1993 Apr;108(4):967-73. doi: 10.1111/j.1476-5381.1993.tb13493.x. PMID: 8485635;
PMCID: PMC1908163.
263: Hewett K, Dickenson AH, McQuay HJ. Lack of effect of morphine-3-glucuronide
on the spinal antinociceptive actions of morphine in the rat: an
electrophysiological study. Pain. 1993 Apr;53(1):59-63. doi:
10.1016/0304-3959(93)90056-u. PMID: 8316391.
264: Chapman V, Dickenson AH. The effects of sandostatin and somatostatin on
nociceptive transmission in the dorsal horn of the rat spinal cord.
Neuropeptides. 1992 Nov;23(3):147-52. doi: 10.1016/0143-4179(92)90115-d. PMID:
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265: Chapman V, Dickenson AH. The spinal and peripheral roles of bradykinin and
prostaglandins in nociceptive processing in the rat. Eur J Pharmacol. 1992 Sep
4;219(3):427-33. doi: 10.1016/0014-2999(92)90484-l. PMID: 1425970.
266: Stanfa LC, Sullivan AF, Dickenson AH. Alterations in neuronal excitability
and the potency of spinal mu, delta and kappa opioids after carrageenan-induced
inflammation. Pain. 1992 Sep;50(3):345-54. doi: 10.1016/0304-3959(92)90040-i.
PMID: 1280804.
267: Kalso EA, Sullivan AF, McQuay HJ, Dickenson AH. Spinal antinociception by
Tyr-D-Ser(otbu)-Gly-Phe-Leu-Thr, a selective delta-opioid receptor agonist. Eur
J Pharmacol. 1992 May 27;216(1):97-101. doi: 10.1016/0014-2999(92)90214-o. PMID:
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268: Sullivan AF, Kalso EA, McQuay HJ, Dickenson AH. Evidence for the
involvement of the mu but not delta opioid receptor subtype in the synergistic
interaction between opioid and alpha 2 adrenergic antinociception in the rat
spinal cord. Neurosci Lett. 1992 May 11;139(1):65-8. doi:
10.1016/0304-3940(92)90859-6. PMID: 1357605.
269: Sullivan AF, Kalso EA, McQuay HJ, Dickenson AH. The antinociceptive actions
of dexmedetomidine on dorsal horn neuronal responses in the anaesthetized rat.
Eur J Pharmacol. 1992 Apr 29;215(1):127-33. doi: 10.1016/0014-2999(92)90617-d.
PMID: 1355441.
270: Fraser HM, Chapman V, Dickenson AH. Spinal local anaesthetic actions on
afferent evoked responses and wind-up of nociceptive neurones in the rat spinal
cord: combination with morphine produces marked potentiation of antinociception.
Pain. 1992 Apr;49(1):33-41. doi: 10.1016/0304-3959(92)90185-e. PMID: 1594281.
271: Haley JE, Dickenson AH, Schachter M. Electrophysiological evidence for a
role of nitric oxide in prolonged chemical nociception in the rat.
Neuropharmacology. 1992 Mar;31(3):251-8. doi: 10.1016/0028-3908(92)90175-o.
PMID: 1630593.
272: Chapman V, Dickenson AH. The combination of NMDA antagonism and morphine
produces profound antinociception in the rat dorsal horn. Brain Res. 1992 Feb
28;573(2):321-3. doi: 10.1016/0006-8993(92)90780-d. PMID: 1387029.
273: Kalliomäki J, Schouenborg J, Dickenson AH. Differential Effects of a
Distant Noxious Stimulus on Hindlimb Nociceptive Withdrawal Reflexes in the Rat.
Eur J Neurosci. 1992;4(7):648-652. doi: 10.1111/j.1460-9568.1992.tb00173.x.
PMID: 12106328.
274: Magnuson DS, Dickenson AH. Lamina-specific effects of morphine and naloxone
in dorsal horn of rat spinal cord in vitro. J Neurophysiol. 1991
Dec;66(6):1941-50. doi: 10.1152/jn.1991.66.6.1941. PMID: 1812227.
275: Dickenson AH, Dray A. Selective antagonism of capsaicin by capsazepine:
evidence for a spinal receptor site in capsaicin-induced antinociception. Br J
Pharmacol. 1991 Dec;104(4):1045-9. doi: 10.1111/j.1476-5381.1991.tb12547.x.
PMID: 1810591; PMCID: PMC1908854.
276: Dickenson AH, Sullivan AF, Stanfa LC, McQuay HJ. Dextromethorphan and
levorphanol on dorsal horn nociceptive neurones in the rat. Neuropharmacology.
1991 Dec;30(12A):1303-8. doi: 10.1016/0028-3908(91)90027-9. PMID: 1787884.
277: Sullivan AF, Kalso EA, McQuay HJ, Dickenson AH. FLFQPQRF-amide modulates
alpha 2-adrenergic antinociception in the rat dorsal horn in vivo. Brain Res.
1991 Oct 25;562(2):327-8. doi: 10.1016/0006-8993(91)90640-h. PMID: 1685347.
278: Dickenson AH, Sullivan AF. NMDA receptors and central hyperalgesic states.
Pain. 1991 Sep;46(3):344-6. doi: 10.1016/0304-3959(91)90118-h. PMID: 1836867.
279: Dickenson AH. Capsaicin: gaps in our knowledge start to be filled. Trends
Neurosci. 1991 Jul;14(7):265-6. doi: 10.1016/0166-2236(91)90133-f. PMID:
1719669.
280: Dickenson AH. Mechanisms of the analgesic actions of opiates and opioids.
Br Med Bull. 1991 Jul;47(3):690-702. doi: 10.1093/oxfordjournals.bmb.a072501.
PMID: 1665377.
281: Sullivan AF, Dickenson AH. Electrophysiologic studies on the spinal
antinociceptive action of kappa opioid agonists in the adult and 21-day-old rat.
J Pharmacol Exp Ther. 1991 Mar;256(3):1119-25. PMID: 2005577.
282: Dickenson AH, Aydar E. Antagonism at the glycine site on the NMDA receptor
reduces spinal nociception in the rat. Neurosci Lett. 1991 Jan 2;121(1-2):263-6.
doi: 10.1016/0304-3940(91)90700-4. PMID: 1826945.
283: Dickenson AH. Recent advances in the physiology and pharmacology of pain:
plasticity and its implications for clinical analgesia. J Psychopharmacol. 1991
Jan;5(4):342-51. doi: 10.1177/026988119100500424. PMID: 22282839.
284: Dickenson AH, Sullivan AF, McQuay HJ. Intrathecal etorphine, fentanyl and
buprenorphine on spinal nociceptive neurones in the rat. Pain. 1990
Aug;42(2):227-34. doi: 10.1016/0304-3959(90)91166-g. PMID: 2247319.
285: Magnuson DS, Sullivan AF, Simonnet G, Roques BP, Dickenson AH. Differential
interactions of cholecystokinin and FLFQPQRF-NH2 with mu and delta opioid
antinociception in the rat spinal cord. Neuropeptides. 1990 Aug;16(4):213-8.
doi: 10.1016/0143-4179(90)90065-7. PMID: 2177165.
286: Dickenson AH. A cure for wind up: NMDA receptor antagonists as potential
analgesics. Trends Pharmacol Sci. 1990 Aug;11(8):307-9. doi:
10.1016/0165-6147(90)90228-z. PMID: 2168102.
287: Haley JE, Sullivan AF, Dickenson AH. Evidence for spinal N-methyl-D-
aspartate receptor involvement in prolonged chemical nociception in the rat.
Brain Res. 1990 Jun 4;518(1-2):218-26. doi: 10.1016/0006-8993(90)90975-h. PMID:
1975214.
288: McQuay HJ, Dickenson AH. Implications of nervous system plasticity for pain
management. Anaesthesia. 1990 Feb;45(2):101-2. doi:
10.1111/j.1365-2044.1990.tb14270.x. PMID: 2157345.
289: Dickenson AH, Sullivan AF. Differential effects of excitatory amino acid
antagonists on dorsal horn nociceptive neurones in the rat. Brain Res. 1990 Jan
1;506(1):31-9. doi: 10.1016/0006-8993(90)91195-m. PMID: 1967963.
290: Poree LR, Dickenson AH, Wei ET. Corticotropin-releasing factor inhibits the
response of trigeminal neurons to noxious heat. Brain Res. 1989 Nov
20;502(2):349-55. doi: 10.1016/0006-8993(89)90631-8. PMID: 2819471.
291: Sullivan AF, Dickenson AH, Roques BP. Delta-opioid mediated inhibitions of
acute and prolonged noxious-evoked responses in rat dorsal horn neurones. Br J
Pharmacol. 1989 Nov;98(3):1039-49. doi: 10.1111/j.1476-5381.1989.tb14636.x.
PMID: 2556199; PMCID: PMC1854772.
292: Smallman K, Dickenson AH, Halsey MJ. Electrophysiological studies on the
effects of opiates on dorsal horn nociceptive neurones at 51 atmospheres
absolute. Pain. 1989 Jul;38(1):57-64. doi: 10.1016/0304-3959(89)90073-0. PMID:
2780064.
293: Sullivan AF, McQuay HJ, Bailey D, Dickenson AH. The spinal antinociceptive
actions of morphine metabolites morphine-6-glucuronide and normorphine in the
rat. Brain Res. 1989 Mar 20;482(2):219-24. doi: 10.1016/0006-8993(89)91184-0.
PMID: 2706485.
294: Haley JE, Dickenson AH, Schachter M. Electrophysiological evidence for a
role of bradykinin in chemical nociception in the rat. Neurosci Lett. 1989 Feb
13;97(1-2):198-202. doi: 10.1016/0304-3940(89)90163-8. PMID: 2537479.
295: McQuay HJ, Sullivan AF, Smallman K, Dickenson AH. Intrathecal opioids,
potency and lipophilicity. Pain. 1989 Jan;36(1):111-5. doi:
10.1016/0304-3959(89)90118-8. PMID: 2537486.
296: Sullivan AF, Dickenson AH. Electrophysiological studies on the spinal
effects of dermorphin, an endogenous mu-opioid agonist. Brain Res. 1988 Sep
27;461(1):182-5. doi: 10.1016/0006-8993(88)90738-x. PMID: 2906269.
297: Dickenson AH, Sullivan AF, Roques BP. Evidence that endogenous enkephalins
and a delta opioid receptor agonist have a common site of action in spinal
antinociception. Eur J Pharmacol. 1988 Apr 13;148(3):437-9. doi:
10.1016/0014-2999(88)90123-9. PMID: 2838307.
298: Zajac JM, Dauge V, Dickenson AH, Roques BP. Enképhalines et analgésie
[Enkephalins and analgesia]. Agressologie. 1988 Feb;29(2):67-70. French. PMID:
2841881.
299: Dickenson AH, Sullivan AF. Peripheral origins and central modulation of
subcutaneous formalin-induced activity of rat dorsal horn neurones. Neurosci
Lett. 1987 Dec 16;83(1-2):207-11. doi: 10.1016/0304-3940(87)90242-4. PMID:
3441298.
300: Dickenson AH, Le Bars D. Lack of evidence for increased descending
inhibition on the dorsal horn of the rat following periaqueductal grey morphine
microinjections. Br J Pharmacol. 1987 Oct;92(2):271-80. doi:
10.1111/j.1476-5381.1987.tb11321.x. PMID: 3676594; PMCID: PMC1853651.
301: Dickenson AH, Sullivan AF. Subcutaneous formalin-induced activity of dorsal
horn neurones in the rat: differential response to an intrathecal opiate
administered pre or post formalin. Pain. 1987 Sep;30(3):349-60. doi:
10.1016/0304-3959(87)90023-6. PMID: 3670880.
302: Dickenson AH, Sullivan AF. Evidence for a role of the NMDA receptor in the
frequency dependent potentiation of deep rat dorsal horn nociceptive neurones
following C fibre stimulation. Neuropharmacology. 1987 Aug;26(8):1235-8. doi:
10.1016/0028-3908(87)90275-9. PMID: 2821443.
303: Knox RJ, Dickenson AH. Effects of selective and non-selective kappa-opioid
receptor agonists on cutaneous C-fibre-evoked responses of rat dorsal horn
neurones. Brain Res. 1987 Jul 7;415(1):21-9. doi: 10.1016/0006-8993(87)90265-4.
PMID: 2887243.
304: Sullivan AF, Dashwood MR, Dickenson AH. Alpha 2-adrenoceptor modulation of
nociception in rat spinal cord: location, effects and interactions with
morphine. Eur J Pharmacol. 1987 Jun 19;138(2):169-77. doi:
10.1016/0014-2999(87)90430-4. PMID: 3040431.
305: Dickenson AH, Sullivan AF, Knox R, Zajac JM, Roques BP. Opioid receptor
subtypes in the rat spinal cord: electrophysiological studies with mu- and
delta-opioid receptor agonists in the control of nociception. Brain Res. 1987
Jun 9;413(1):36-44. doi: 10.1016/0006-8993(87)90151-x. PMID: 3036317.
306: Dickenson AH, Sullivan AF, Fournie-Zaluski MC, Roques BP. Prevention of
degradation of endogenous enkephalins produces inhibition of nociceptive
neurones in rat spinal cord. Brain Res. 1987 Apr 7;408(1-2):185-91. doi:
10.1016/0006-8993(87)90370-2. PMID: 3474047.
307: Dickenson AH, Knox RJ. Antagonism of mu-opioid receptor-mediated
inhibitions of nociceptive neurones by U50488H and dynorphin A1-13 in the rat
dorsal horn. Neurosci Lett. 1987 Mar 31;75(2):229-34. doi:
10.1016/0304-3940(87)90302-8. PMID: 2883617.
308: Dickenson AH, Le Bars D. Supraspinal morphine and descending inhibitions
acting on the dorsal horn of the rat. J Physiol. 1987 Mar;384:81-107. doi:
10.1113/jphysiol.1987.sp016444. PMID: 3309265; PMCID: PMC1192252.
309: Dickenson AH, Sullivan A, Feeney C, Fournie-Zaluski MC, Roques BP. Evidence
that endogenous enkephalins produce delta-opiate receptor mediated neuronal
inhibitions in rat dorsal horn. Neurosci Lett. 1986 Dec 12;72(2):179-82. doi:
10.1016/0304-3940(86)90076-5. PMID: 3027626.
310: Dickenson AH, Goldsmith G. Evidence for a role of 5-hydroxytryptamine in
the responses of rat raphe magnus neurones to peripheral noxious stimuli.
Neuropharmacology. 1986 Aug;25(8):863-8. doi: 10.1016/0028-3908(86)90012-2.
PMID: 3022179.
311: Dickenson AH. Enkephalins. A new approach to pain relief? Nature. 1986 Apr
24-30;320(6064):681-2. doi: 10.1038/320681a0. PMID: 3517655.
312: Dickenson AH, Sullivan AF. Electrophysiological studies on the effects of
intrathecal morphine on nociceptive neurones in the rat dorsal horn. Pain. 1986
Feb;24(2):211-22. doi: 10.1016/0304-3959(86)90044-8. PMID: 3754322.
313: Fournié-Zaluski MC, Bourgoin S, Cesselin F, Hamon M, Le Bars D, Dickenson
AH, Roques BP. Increase in met-enkephalin level and antinociceptive effects
induced by kelatorphan in the rat spinal cord. NIDA Res Monogr. 1986;75:454-6.
PMID: 3123963.
314: Dickenson AH, Brewer CM, Hayes NA. Effects of topical baclofen on C fibre-
evoked neuronal activity in the rat dorsal horn. Neuroscience. 1985
Feb;14(2):557-62. doi: 10.1016/0306-4522(85)90310-0. PMID: 2986041.
315: Dickenson AH, Le Bars D. Diffuse noxious inhibitory controls (DNIC) involve
trigeminothalamic and spinothalamic neurones in the rat. Exp Brain Res.
1983;49(2):174-80. doi: 10.1007/BF00238577. PMID: 6832255.
316: Dickenson AH, Le Bars D. Morphine microinjections into periaqueductal grey
matter of the rat: effects on dorsal horn neuronal responses to C-fibre activity
and diffuse noxious inhibitory controls. Life Sci. 1983;33 Suppl 1:549-52. doi:
10.1016/0024-3205(83)90562-3. PMID: 6664236.
317: Chitour D, Dickenson AH, Le Bars D. Pharmacological evidence for the
involvement of serotonergic mechanisms in diffuse noxious inhibitory controls
(DNIC). Brain Res. 1982 Mar 25;236(2):329-37. doi: 10.1016/0006-8993(82)90718-1.
PMID: 6978166.
318: Dickenson AH, Rivot JP, Chaouch A, Besson JM, Le Bars D. Diffuse noxious
inhibitory controls (DNIC) in the rat with or without pCPA pretreatment. Brain
Res. 1981 Jul 20;216(2):313-21. doi: 10.1016/0006-8993(81)90133-5. PMID:
6454457.
319: Dickenson AH, Le Bars D, Besson JM. Endogenous opiates and nociception: a
possible functional role in both pain inhibition and detection as revealed by
intrathecal naloxone. Neurosci Lett. 1981 Jul 2;24(2):161-4. doi:
10.1016/0304-3940(81)90241-x. PMID: 7254713.
320: Le Bars D, Chitour D, Kraus E, Clot AM, Dickenson AH, Besson JM. The effect
of systemic morphine upon diffuse noxious inhibitory controls (DNIC) in the rat:
evidence for a lifting of certain descending inhibitory controls of dorsal horn
convergent neurones. Brain Res. 1981 Jun 29;215(1-2):257-74. doi:
10.1016/0006-8993(81)90506-0. PMID: 7260590.
321: Dickenson AH, Hellon RF, Woolf CJ. Tooth pulp input to the spinal
trigeminal nucleus: a comparison of inhibitions following segmental and raphe
magnus stimulation. Brain Res. 1981 Jun 9;214(1):73-87. doi:
10.1016/0006-8993(81)90439-x. PMID: 7237167.
322: Dawson NJ, Dickenson AH, Hellon RF, Woolf CJ. Inhibitory controls on
thermal neurones in the spinal trigeminal nucleus of cats and rats. Brain Res.
1981 Mar 30;209(2):440-5. doi: 10.1016/0006-8993(81)90167-0. PMID: 7225804.
323: Le Bars D, Dickenson AH, Rivot JP, Chitour D, Chaouch A, Kraus E, Besson
JM. Les systèmes sérotoninergiques bulbo-spinaux jouent-ils un rôle dans la
détection des messages nociceptifs? [Are bulbo-spinal serotonergic systems
involved in the detection of nociceptive messages? (author's transl)]. J Physiol
(Paris). 1981;77(2-3):463-71. French. PMID: 6270318.
324: Dickenson AH, Le Bars D, Besson JM. Diffuse noxious inhibitory controls
(DNIC). Effects on trigeminal nucleus caudalis neurones in the rat. Brain Res.
1980 Nov 3;200(2):293-305. doi: 10.1016/0006-8993(80)90921-x. PMID: 7417817.
325: Le Bars D, Chitour D, Kraus E, Dickenson AH, Besson JM. Dépression par la
morphine de certains contrôles inhibiteurs descendants qui modulent, chez le
rat, la transmission des messages nociceptifs au niveau spinal [Depression by
morphine of various descending inhibitory controls modulating the transmission
of nociceptive information at the spinal level in the rat]. C R Seances Acad Sci
D. 1980 Sep 29;291(4):433-6. French. PMID: 6777065.
326: Le Bars D, Dickenson AH, Besson JM. Microinjection of morphine within
nucleus raphe magnus and dorsal horn neurone activities related to nociception
in the rat. Brain Res. 1980 May 12;189(2):467-81. doi:
10.1016/0006-8993(80)90106-7. PMID: 6245766.
327: Le Bars D, Rivot JP, Dickenson AH, Chaouch A, Besson JM. Rôle de la
sérontonine dans les contrôles inhibiteurs diffus induits par des stimulations
nociceptives [Role of serotonin in the diffuse inhibitory controls induced by
nociceptive stimulation]. C R Seances Acad Sci D. 1980 Jan 28;290(4):379-82.
French. PMID: 6444550.
328: Le Bars D, Chitour D, Kraus E, Dickenson AH, Besson JM. Effect of naloxone
upon diffuse noxious inhibitory controls (DNIC) in the rat. Brain Res. 1981 Jan
12;204(2):387-402. doi: 10.1016/0006-8993(81)90597-7. PMID: 6257327.
329: Dickenson AH, Fardin V, Le Bars D, Besson JM. Antinociceptive action
following microinjection of methionine-enkephalin in the nucleus raphe magnus of
the rat. Neurosci Lett. 1979 Dec;15(2-3):265-70. doi:
10.1016/0304-3940(79)96124-x. PMID: 530531.
330: Dickenson AH, Oliveras JL, Besson JM. Role of the nucleus raphe magnus in
opiate analgesia as studied by the microinjection technique in the rat. Brain
Res. 1979 Jul 6;170(1):95-111. doi: 10.1016/0006-8993(79)90943-0. PMID: 223722.
331: Besson JM, Dickenson AH, Le Bars D. Plurisegmental noxious inhibitory
controls on rat dorsal horn convergent neurones [proceedings]. J Physiol. 1979
Jul;292:41P-42P. PMID: 490372.
332: Le Bars D, Dickenson AH, Besson JM. Diffuse noxious inhibitory controls
(DNIC). II. Lack of effect on non-convergent neurones, supraspinal involvement
and theoretical implications. Pain. 1979 Jun;6(3):305-27. doi:
10.1016/0304-3959(79)90050-2. PMID: 460936.
333: Le Bars D, Dickenson AH, Besson JM. Diffuse noxious inhibitory controls
(DNIC). I. Effects on dorsal horn convergent neurones in the rat. Pain. 1979
Jun;6(3):283-304. doi: 10.1016/0304-3959(79)90049-6. PMID: 460935.
334: Dickenson AH, Hellon RF, Taylor DC. Facial thermal input to the trigeminal
spinal nucleus of rabbits and rats. J Comp Neurol. 1979 May 1;185(1):203-9. doi:
10.1002/cne.901850112. PMID: 429614.
335: Dickenson AH, Oliveras JL, Besson JM. Rôle du noyau Raphé Magnus dans
l'analgésie morphinique : Etudes par microinjections intracérébrales chez le rat
[Role of the Raphe Magnus nucleus in morphine analgesia : studies with
intracerebral microinjections in the rat]. C R Acad Hebd Seances Acad Sci D.
1978 Oct 23;287(10):955-8. French. PMID: 106979.
336: Dickenson AH. Specific responses of rat raphé neurones to skin temperature.
J Physiol. 1977 Dec;273(1):277-93. doi: 10.1113/jphysiol.1977.sp012094. PMID:
599422; PMCID: PMC1353739.
337: Deakin JF, Dickenson AH, Dostrovsky JO. Morphine effects on rat raphé
magnus neurones [proceedings]. J Physiol. 1977 May;267(1):43P-45P. PMID: 559757.